User profiles for A. L. Bruzos
Alicia L. BruzosBSc. in Biology; MSc. in Bioinformatics; PhD. in Molecular Medicine Verified email at crick.ac.uk Cited by 2145 |
[HTML][HTML] Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
About half of all cancers have somatic integrations of retrotransposons. Here, to characterize
their role in oncogenesis, we analyzed the patterns and mechanisms of somatic …
their role in oncogenesis, we analyzed the patterns and mechanisms of somatic …
Somatic evolution of marine transmissible leukemias in the common cockle, Cerastoderma edule
Transmissible cancers are malignant cell lineages that spread clonally between individuals.
Several such cancers, termed bivalve transmissible neoplasia (BTN), induce leukemia-like …
Several such cancers, termed bivalve transmissible neoplasia (BTN), induce leukemia-like …
[HTML][HTML] Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
…, B Rodriguez-Martin, A Oitaben, AL Bruzos… - Nature …, 2021 - nature.com
Most cancers are characterized by the somatic acquisition of genomic rearrangements
during tumour evolution that eventually drive the oncogenesis. Here, using multiplatform …
during tumour evolution that eventually drive the oncogenesis. Here, using multiplatform …
[HTML][HTML] Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
In the published version of this paper, the members of the Pan-Cancer Analysis of Whole
Genomes (PCAWG) Consortium were listed in the Supplementary Information; however, these …
Genomes (PCAWG) Consortium were listed in the Supplementary Information; however, these …
Mitochondrial genome sequencing of marine leukaemias reveals cancer contagion between clam species in the Seas of Southern Europe
… To address these questions, Garcia- Souto, Bruzos, Díaz et al. gathered over 400 … To
determine whether the cancer still affected both species, Garcia- Souto, Bruzos, Díaz et al. …
determine whether the cancer still affected both species, Garcia- Souto, Bruzos, Díaz et al. …
Germline determinants of the somatic mutation landscape in 2,642 cancer genomes
Cancers develop through somatic mutagenesis, however germline genetic variation can
markedly contribute to tumorigenesis via diverse mechanisms. We discovered and phased 88 …
markedly contribute to tumorigenesis via diverse mechanisms. We discovered and phased 88 …
Assessing the elemental fingerprints of cockle shells (Cerastoderma edule) to confirm their geographic origin from regional to international spatial scales
Geographic origin is directly linked to the quality and commercial value of bivalves. The
globalization of the seafood trade and the increasing number of fraudulent practices in the …
globalization of the seafood trade and the increasing number of fraudulent practices in the …
[HTML][HTML] The first high-density genetic map of common cockle (Cerastoderma edule) reveals a major QTL controlling shell color variation
Shell color shows broad variation within mollusc species and despite information on the
genetic pathways involved in shell construction and color has recently increased, more studies …
genetic pathways involved in shell construction and color has recently increased, more studies …
[HTML][HTML] Mosaic BRAF Fusions Are a Recurrent Cause of Congenital Melanocytic Nevi Targetable by MAPK Pathway Inhibition
SB Martin, S Polubothu, AL Bruzos, G Kelly… - Journal of Investigative …, 2024 - Elsevier
Among children with multiple congenital melanocytic nevi, 25% have no established genetic
cause, of whom many develop a hyperproliferative and severely pruritic phenotype resistant …
cause, of whom many develop a hyperproliferative and severely pruritic phenotype resistant …
The evolution of two transmissible leukaemias colonizing the coasts of Europe
Transmissible cancers are malignant cell clones that spread among individuals through
transfer of living cancer cells. Several such cancers, collectively known as bivalve transmissible …
transfer of living cancer cells. Several such cancers, collectively known as bivalve transmissible …