User profiles for A. M. Krachler

Anne Marie Krachler

Associate Professor, Microbiology and Molecular Genetics, UT Health Science Center …
Verified email at uth.tmc.edu
Cited by 2895

Mechanisms of outer membrane vesicle entry into host cells

EJ O'donoghue, AM Krachler - Cellular microbiology, 2016 - Wiley Online Library
… We would like to thank the Krachler lab for critical reading and comments on drafts of this
manuscript. EJO is funded by a BBSRC MIBTP scholarship. AMK is funded by BBSRC grants …

Targeting the bacteria–host interface: strategies in anti-adhesion therapy

AM Krachler, K Orth - Virulence, 2013 - Taylor & Francis
Krachler AM, Orth K. Functional characterization of the interaction between bacterial adhesin
multivalent adhesion molecule 7 (MAM7) protein and its host cell ligands. J Biol Chem 2011…

Manipulation of kinase signaling by bacterial pathogens

AM Krachler, AR Woolery, K Orth - Journal of Cell Biology, 2011 - rupress.org
… Orth, AM Krachler, and AR Woolery are supported by grants from National Institutes of
Health, National Institute for Allergy and Infectious Disease (R01-AI056404 and R01-AI087808) …

Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gram-negative pathogens

AM Krachler, H Ham, K Orth - Proceedings of the National …, 2011 - National Acad Sciences
The initial binding of bacteria to host cells is crucial to the delivery of virulence factors and
thus is a key determinant of the pathogen's success. We report a multivalent adhesion …

Outer membrane vesicle-host cell interactions

…, NM O'Brien-Simpson, AM Krachler - Microbiology …, 2019 - Am Soc Microbiol
… We thank the O’Brien-Simpson and Krachler labs for helpful comments and critical … O’Donoghue
EJ, Krachler AM. 2016. Mechanisms of outer membrane vesicle … Anne Marie Krachler

[PDF][PDF] Type III effector VopC mediates invasion for Vibrio species

L Zhang, AM Krachler, CA Broberg, Y Li, H Mirzaei… - Cell reports, 2012 - cell.com
Vibrio spp. are associated with infections caused by contaminated food and water. A type III
secretion system (T3SS2) is a shared feature of all clinical isolates of V. parahaemolyticus …

Against the tide: the role of bacterial adhesion in host colonization

DH Stones, AM Krachler - Biochemical Society Transactions, 2016 - portlandpress.com
… Daniel Henry Stones, Anne Marie Krachler; Against the tide: the role of bacterial
adhesion in host … The topic was more comprehensively reviewed by Stones and Krachler [57]. …

Host attachment and fluid shear are integrated into a mechanical signal regulating virulence in Escherichia coli O157:H7

…, R Shah, SJ Busby, AM Krachler - Proceedings of the …, 2015 - National Acad Sciences
Enterohemorrhagic Escherichia coli (EHEC) is a foodborne pathogen causing hemorrhagic
colitis and hemolytic uremic syndrome. EHEC colonizes the intestinal tract through a range …

The zebrafish as a model for gastrointestinal tract–microbe interactions

…, MA Odem, GT Eisenhoffer, AM Krachler - Cellular …, 2020 - Wiley Online Library
… We thank members of the Krachler and Eisenhoffer labs for useful comments on earlier
versions of the manuscript. We thank Jordan Pietz (University of Texas MD Anderson Cancer …

[HTML][HTML] Functional characterization of the interaction between bacterial adhesin multivalent adhesion molecule 7 (MAM7) protein and its host cell ligands

AM Krachler, K Orth - Journal of Biological Chemistry, 2011 - ASBMB
The ability of a pathogen to rapidly form a stable interaction with the host cell surface is key
to its success. Bacterial pathogens use a repertoire of virulence factors, but their efficient use …