miR‐21: a small multi‐faceted RNA
AM Krichevsky, G Gabriely - Journal of cellular and molecular …, 2009 - Wiley Online Library
… We thank Krichevsky laboratory members for insightful discussions and Dr. Kai-Christian
Sonntag for his careful reading of the manuscript. The work in the laboratory is supported by …
Sonntag for his careful reading of the manuscript. The work in the laboratory is supported by …
Multidimensional communication in the microenvirons of glioblastoma
Glioblastomas are heterogeneous and invariably lethal tumours. They are characterized by
genetic and epigenetic variations among tumour cells, which makes the development of …
genetic and epigenetic variations among tumour cells, which makes the development of …
[PDF][PDF] The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research
The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
…, L Gainche, WT Curry Jr, BS Carter, AM Krichevsky… - Nature cell …, 2008 - nature.com
Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and
angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain …
angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain …
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
… JA Chan and AM Krichevsky contributed equally to this work. … (AM Krichevsky), and
Mahoney Center for Neuro-Oncology Fellowship at the Dana-Farber Cancer Institute (JA Chan). …
Mahoney Center for Neuro-Oncology Fellowship at the Dana-Farber Cancer Institute (JA Chan). …
A microRNA array reveals extensive regulation of microRNAs during brain development
Several hundred microRNAs (miRNAs) have recently been cloned from a wide range of
organisms across phylogeny. Despite the high degree of conservation of miRNAs, their …
organisms across phylogeny. Despite the high degree of conservation of miRNAs, their …
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
…, J Burchard, PS Linsley, AM Krichevsky - … and cellular biology, 2008 - Taylor & Francis
Substantial data indicate that microRNA 21 (miR-21) is significantly elevated in glioblastoma
(GBM) and in many other tumors of various origins. This microRNA has been implicated in …
(GBM) and in many other tumors of various origins. This microRNA has been implicated in …
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU. 1 pathway
…, T Veremeyko, N Barteneva, AM Krichevsky… - Nature medicine, 2011 - nature.com
MicroRNAs are a family of regulatory molecules involved in many physiological processes,
including differentiation and activation of cells of the immune system. We found that brain-…
including differentiation and activation of cells of the immune system. We found that brain-…
Specific microRNAs modulate embryonic stem cell–derived neurogenesis
AM Krichevsky, KC Sonntag, O Isacson, KS Kosik - Stem cells, 2006 - academic.oup.com
MicroRNAs (miRNAs) are recently discovered small non-coding transcripts with a broad
spectrum of functions described mostly in invertebrates. As post-transcriptional regulators of …
spectrum of functions described mostly in invertebrates. As post-transcriptional regulators of …
[PDF][PDF] Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation
AM Krichevsky, KS Kosik - Neuron, 2001 - cell.com
RNA granules are a macromolecular structure observed in neurons, where they serve as
motile units that translocate mRNAs. Isolated RNA granules are highly enriched in Staufen …
motile units that translocate mRNAs. Isolated RNA granules are highly enriched in Staufen …