Though many neuroscientific methods have been brought to bear in the search for functional
specializations within prefrontal cortex, little consensus has emerged. To assess the …

Functional imaging gives us increasingly detailed information about the location of brain
activity. To use this information, we need a clear conception of the meaning of location data. …

The anterior prefrontal cortex (aPFC), or Brodmann area 10, is one of the least well understood
regions of the human brain. Work with non-human primates has provided almost no …

One of the most popular experimental paradigms for functional neuroimaging studies of working
memory has been the n‐back task, in which subjects are asked to monitor the identity or …

We used functional magnetic resonance imaging to demonstrate preserved conscious
awareness in a patient fulfilling the criteria for a diagnosis of vegetative state. When asked to …

Twenty-six patients with unilateral or bilateral frontal lobe excisions were compared with age
and IQ matched controls on a computerized battery of tests of spatial working memory and …

Background The differential diagnosis of disorders of consciousness is challenging. The
rate of misdiagnosis is approximately 40%, and new methods are required to complement …

‘Brain training’, or the goal of improved cognitive function through the regular use of computerized
tests, is a multimillion-pound industry 1 , yet in our view scientific evidence to support …

There is growing interest regarding the role of the right inferior frontal gyrus (RIFG) during a
particular form of executive control referred to as response inhibition. However, tasks used to …

We review the nosological criteria and functional neuroanatomical basis for brain death,
coma, vegetative state, minimally conscious state, and the locked-in state. Functional …