Acute cystitis is one of the most commonly encountered bacterial infections and is responsible
for substantial morbidity and high medical costs in the United States and across the globe. …

Antiretroviral therapy (ART) has rendered HIV-1 infection a treatable illness; however, ART
is not curative owing to the persistence of replication-competent, latent proviruses in long-…

Therapeutic strategies are being clinically tested either to eradicate latent HIV reservoirs or
to achieve virologic control in the absence of antiretroviral therapy. Attaining this goal will …

Objective To describe detection of severe acute respiratory syndrome (SARS)–coronavirus
2 (CoV-2) in seminal fluid of patients recovering from coronavirus disease 2019 (COVID-19) …

Background. Transcriptionally silent human immunodeficiency virus type 1 (HIV-1) DNA
persists in resting memory CD4 + T cells despite antiretroviral therapy. In a primary cell model, …

Combination antiretroviral therapy (ART) is able to suppress HIV-1 replication to undetectable
levels. However, the persistence of latent viral reservoirs allows for a rebound of viral load …

Antiretroviral therapy (ART) suppresses viral replication in people living with HIV. Yet, infected
cells persist for decades on ART and viremia returns if ART is stopped. Persistence has …

… , AM Spivak). Total CD4 + T cells were purified via negative magnetic bead selection
using a total CD4 + T cell–negative isolation kit (STEMCELL) according to the manufacturer’s …

Antiretroviral therapy (ART) has rendered HIV-1 infection a manageable illness for those
with access to treatment. However, ART does not lead to viral eradication owing to the …

The human immunodeficiency virus type 1 (HIV-1) latent reservoir in resting CD4 + T cells
represents a major barrier to viral eradication. Small compounds capable of latency reversal …