User profiles for A. M. Tseng
Alex M TsengGenentech Verified email at gene.com Cited by 200 |
The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants
…, WC Nelson, WR Ott, JP Robinson, AM Tsang… - Journal of exposure …, 2001 - nature.com
… is in a residence from about 11 PM to 5 AM, and, as expected, the largest proportions of
respondents in schools, public buildings, offices, and factories occur between 7 AM and 5 PM. …
respondents in schools, public buildings, offices, and factories occur between 7 AM and 5 PM. …
Structural and functional characterization of G protein–coupled receptors with deep mutational scanning
The >800 human G protein–coupled receptors (GPCRs) are responsible for transducing
diverse chemical stimuli to alter cell state- and are the largest class of drug targets. Their myriad …
diverse chemical stimuli to alter cell state- and are the largest class of drug targets. Their myriad …
[HTML][HTML] Plasma miRNA profiles in pregnant women predict infant outcomes following prenatal alcohol exposure
S Balaraman, JJ Schafer, AM Tseng, W Wertelecki… - PLoS …, 2016 - journals.plos.org
Fetal alcohol spectrum disorders (FASD) are difficult to diagnose since many heavily
exposed infants, at risk for intellectual disability, do not exhibit craniofacial dysmorphology or …
exposed infants, at risk for intellectual disability, do not exhibit craniofacial dysmorphology or …
Ethanol exposure increases miR‐140 in extracellular vesicles: implications for fetal neural stem cell proliferation and maturation
AM Tseng, DD Chung, MR Pinson… - Alcoholism: Clinical …, 2019 - Wiley Online Library
Background Neural stem cells ( NSC s) generate most of the neurons of the adult brain in
humans, during the mid‐first through second‐trimester period. This critical neurogenic window …
humans, during the mid‐first through second‐trimester period. This critical neurogenic window …
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1
Master regulators, such as the hematopoietic transcription factor (TF) GATA1, play an
essential role in orchestrating lineage commitment and differentiation. However, the precise …
essential role in orchestrating lineage commitment and differentiation. However, the precise …
Transcription factor expression defines subclasses of developing projection neurons highly similar to single-cell RNA-seq subtypes
We are only just beginning to catalog the vast diversity of cell types in the cerebral cortex.
Such categorization is a first step toward understanding how diversification relates to function. …
Such categorization is a first step toward understanding how diversification relates to function. …
[HTML][HTML] Infant circulating MicroRNAs as biomarkers of effect in fetal alcohol spectrum disorders
Prenatal alcohol exposure (PAE) can result in cognitive and behavioral disabilities and
growth deficits. Because alcohol-related neurobehavioral deficits may occur in the absence of …
growth deficits. Because alcohol-related neurobehavioral deficits may occur in the absence of …
Maternal circulating miRNAs that predict infant FASD outcomes influence placental maturation
Prenatal alcohol exposure (PAE), like other pregnancy complications, can result in placental
insufficiency and fetal growth restriction, although the linking causal mechanisms are …
insufficiency and fetal growth restriction, although the linking causal mechanisms are …
Nonprotein-coding RNAs in fetal alcohol spectrum disorders
Early developmental exposure to ethanol, a known teratogen, can result in a range of
neurodevelopmental disorders, collectively referred to as Fetal Alcohol Spectrum Disorders (…
neurodevelopmental disorders, collectively referred to as Fetal Alcohol Spectrum Disorders (…
Prenatal alcohol exposure contributes to negative pregnancy outcomes by altering fetal vascular dynamics and the placental transcriptome
MR Pinson, AM Tseng, A Adams… - Alcoholism: Clinical …, 2022 - Wiley Online Library
Background Prenatal alcohol exposure (PAE) has been shown to alter fetal blood flow in
utero and is also associated with placental insufficiency and intrauterine growth restriction (…
utero and is also associated with placental insufficiency and intrauterine growth restriction (…