There is a general agreement that granulosa cell apoptosis is the cause of antral follicle
attrition. Less clear is whether this pathway is also activated in case of preantral follicle …

In nonprimates the spermatogonial compartment can be subdivided into (morphologically)
undifferentiated spermatogonia and differentiating spermatogonia. Each cycle of the …

Chromatin structure and function are for a large part determined by the six members of the
structural maintenance of chromosomes (SMC) protein family, which form three heterodimeric …

Vitamin A deficiency leads to an arrest of spermatogenesis and a loss of advanced germ cells
in male mice. In the present study, the effects of several retinoids and carotenoids on these …

Loss-of-function mutations in the immunoglobulin superfamily member 1 (IGSF1) gene cause
an X-linked syndrome of central hypothyroidism, macroorchidism, variable prolactin and …

Recently, we have reported that retinoic acid (RA), similarly to retinol acetate, is able to reinitiate
spermatogenesis in vitamin A-deficient rats. Here, we investigated the expression of RA …

The outermost layer of mammalian skin, the stratum corneum, provides the body with a
barrier against transepidermal water loss and penetration of agents from outside. The lipid-rich …

We recently described the ‘spontaneous’ migration of skin dendritic cells out of human split
skin during culture. Since newly infiltrating cells from the circulation are excluded, this in vitro …

… We are grateful to Dr AM Kruisbeek for valuable discussions throughout the work and Dr GM
van Bleek for critical reading of the manuscript. We thank Drs HL Ploegh (MIT, Boston), ICM …

This study examines the in vivo migration of rat skin dendritic cells (including Langerhans
cells) after skin transplantation. As donor animals, PVG-RT7b rats were used. The leukocytes …