Background Non-fatal outcomes of disease and injury increasingly detract from the ability of
the world's population to live in full health, a trend largely attributable to an epidemiological …

Background The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides
an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden …

Background Targeted public health response to obesity in Nigeria is relatively low due to
limited epidemiologic understanding. We aimed to estimate nationwide and sub-national …

Background The scale-up of tobacco control, especially after the adoption of the Framework
Convention for Tobacco Control, is a major public health success story. Nonetheless, …

Background In transitioning from the Millennium Development Goal to the Sustainable
Development Goal era, it is imperative to comprehensively assess progress toward reducing …

Background Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide
summary measures of health across geographies and time that can inform assessments …

Background Established in 2000, Millennium Development Goal 4 (MDG4) catalysed
extraordinary political, financial, and social commitments to reduce under-5 mortality by two-thirds …

Background Timely assessment of the burden of HIV/AIDS is essential for policy setting and
programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD …

Background In September, 2015, the UN General Assembly established the Sustainable
Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 …

13 C metabolic flux analysis (MFA) has made important contributions to our understanding
of the physiology of model strains of E. coli and yeast, and it has been widely used to guide …