Striving toward translation: strategies for reliable fMRI measurement

ML Elliott, AR Knodt, AR Hariri - Trends in cognitive sciences, 2021 - cell.com
fMRI has considerable potential as a translational tool for understanding risk, prioritizing
interventions, and improving the treatment of brain disorders. However, recent studies have …

What is the test-retest reliability of common task-functional MRI measures? New empirical evidence and a meta-analysis

ML Elliott, AR Knodt, D Ireland, ML Morris… - Psychological …, 2020 - journals.sagepub.com
… (by authors ML Elliott and AR Knodt). We included all original… AR Knodt contributed equally
to this work and are joint first authors. A. Caspi, AR Hariri, TE Moffitt, ML Elliott, and AR Knodt

The genetic architecture of the human cerebral cortex

…, S Kelly, M Kikuchi, M Klein, M Knapp, AR Knodt… - Science, 2020 - science.org
INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological, …

[PDF][PDF] A neural biomarker of psychological vulnerability to future life stress

JR Swartz, AR Knodt, SR Radtke, AR Hariri - Neuron, 2015 - cell.com
We all experience a host of common life stressors such as the death of a family member,
medical illness, and financial uncertainty. While most of us are resilient to such stressors, …

[HTML][HTML] General functional connectivity: Shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks

ML Elliott, AR Knodt, M Cooke, MJ Kim, TR Melzer… - Neuroimage, 2019 - Elsevier
Intrinsic connectivity, measured using resting-state fMRI, has emerged as a fundamental tool
in the study of the human brain. However, due to practical limitations, many studies do not …

[HTML][HTML] Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort

ML Elliott, DW Belsky, AR Knodt, D Ireland… - Molecular …, 2021 - nature.com
An individual’s brainAGE is the difference between chronological age and age predicted
from machine-learning models of brain-imaging data. BrainAGE has been proposed as a …

A connectome-wide functional signature of transdiagnostic risk for mental illness

ML Elliott, A Romer, AR Knodt, AR Hariri - Biological psychiatry, 2018 - Elsevier
Background High rates of comorbidity, shared risk, and overlapping therapeutic mechanisms
have led psychopathology research toward transdiagnostic dimensional investigations of …

Structural alterations within cerebellar circuitry are associated with general liability for common mental disorders

AL Romer, AR Knodt, R Houts, BD Brigidi… - Molecular …, 2018 - nature.com
Accumulating mental-health research encourages a shift in focus toward transdiagnostic
dimensional features that are shared across categorical disorders. In support of this shift, recent …

Lower structural integrity of the uncinate fasciculus is associated with a history of child maltreatment and future psychological vulnerability to stress

…, AR Knodt, BD Brigidi, AR Hariri - Development and …, 2015 - cambridge.org
The experience of child maltreatment is a significant risk factor for the development of later
internalizing disorders such as depression and anxiety. This risk is particularly heightened …

[HTML][HTML] Decoding spontaneous emotional states in the human brain

PA Kragel, AR Knodt, AR Hariri, KS LaBar - PLoS biology, 2016 - journals.plos.org
Pattern classification of human brain activity provides unique insight into the neural underpinnings
of diverse mental states. These multivariate tools have recently been used within the …