The receptor for advanced glycation end products (RAGE) is a multiligand transmembrane
receptor implicated in a number of diseases including autoimmune diseases. To further …

Gene expression levels in clonal bacterial groups have been found to be spatially correlated.
These correlations can partly be explained by the shared lineage history of nearby cells, …

Background Scavenger receptors are important components of the innate immune system in
the lung, allowing alveolar macrophages to bind and phagocytose numerous unopsonized …

Chronic obstructive pulmonary disease (COPD) is a debilitating condition resulting from
exposure to pollutants such as cigarette smoke. Pulmonary macrophages secrete a plethora of …

Pulmonary macrophages (MØs) are essential for clearance of inhaled particles, innate
immunity, and lung tissue maintenance. However, the products of activated MØs have also been …

BACKGROUND: Peroxisome proliferator-activated receptor γ (PPAR-γ) expression has not
been evaluated in bronchoalveolar lavage (BAL) cells from allergic asthmatic patients. …

Background: The purpose of the study was to evaluate the use of phospho-Akt in mouse and
human skin as a surrogate target for tumor phospho-Akt to measure the effect of antitumor …

Recent advances in single-cell sequencing technologies enable the generation of large-scale
data sets of paired TCR sequences from patients with autoimmune disease. Methods to …

The NLRP3 inflammasome is a complex multimeric signaling apparatus that regulates production
of the pro-inflammatory cytokine IL-1β. To overcome both the variability among primary …

A case of chronic, progressive avulsion of the anterior superior iliac spine leading to the
formation of a long, attenuated spur of bone in an 18-year-old black male break dancer is …