Nucleoside analogs represent the largest class of small molecule-based antivirals, which
currently form the backbone of chemotherapy of chronic infections caused by HIV, hepatitis B …

The phosphatidylinositol 4-kinases (PI4Ks) synthesize phosphatidylinositol 4-phosphate (PI4P),
a key member of the phosphoinositide family. PI4P defines the membranes of Golgi and …

The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing, nationwide
study of the effects of environmental influences on behavioral and brain development in …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19
pandemic. 2′-O-RNA methyltransferase (MTase) is one of the enzymes of this virus that …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the coronavirus disease 2019 (COVID-19). SARS-CoV-2 is a single-stranded positive-sense …

Neutralizing antibodies that target the receptor-binding domain (RBD) of the SARS-CoV-2
spike protein are among the most promising approaches against COVID-19 1 , 2 . A bispecific …

Sport-related concussion (SRC) is a major health problem, affecting millions of athletes each
year. While the clinical effects of SRC (eg, symptoms and functional impairments) typically …

Monkeypox is a disease with pandemic potential. It is caused by the monkeypox virus (MPXV),
a double-stranded DNA virus from the Poxviridae family, that replicates in the cytoplasm …

There is growing evidence that Zika virus (ZIKV) can cause devastating infant brain defects
and other neurological disorders in humans. However, no specific antiviral therapy is …

The Adolescent Brain Cognitive Development (ABCD) Study ® is a 10-year longitudinal study
of children recruited at ages 9 and 10. A battery of neuroimaging tasks are administered …