Universal computing by DNA origami robots in a living animal

…, E Ben-Ishay, D Levner, S Ittah, A Abu-Horowitz… - Nature …, 2014 - nature.com
Biological systems are collections of discrete molecular objects that move around and
collide with each other. Cells carry out elaborate processes by precisely controlling these …

Visualizing the structure and motion of the long noncoding RNA HOTAIR

…, J Giron, R Unger, E Segal, A Abu-Horowitz… - Rna, 2020 - rnajournal.cshlp.org
Long noncoding RNA molecules (lncRNAs) are estimated to account for the majority of
eukaryotic genomic transcripts, and have been associated with multiple diseases in humans. …

[HTML][HTML] Biodistribution and function of coupled polymer-DNA origami nanostructures

…, A Shapiro, E Gillis, S Barkey, A Abu-Horowitz… - Scientific Reports, 2023 - nature.com
Spatial control over the distribution of therapeutics is a highly desired feature, which could
limit the side effects of many drugs. Here we describe a nanoscale agent, fabricated from a …

[HTML][HTML] Meshing complex macro-scale objects into self-assembling bricks

…, I Hanniel, Y Nikulshin, S Wolfus, A Abu-Horowitz… - Scientific reports, 2015 - nature.com
Self-assembly provides an information-economical route to the fabrication of objects at
virtually all scales. However, there is no known algorithm to program self-assembly in macro-scale…

[HTML][HTML] Fundus albipunctatus: novel mutations and phenotypic description of Israeli patients

…, S Raivech, Y Barkana, A Abu-Horowitz… - Molecular …, 2012 - ncbi.nlm.nih.gov
Methods Twenty patients with FAP from diverse ethnicities underwent ophthalmic and
electroretinogram tests following the International Society for Clinical Electrophysiology of Vision …

Cooperativity-based modeling of heterotypic DNA nanostructure assembly

…, A Hozeh, O Girshevitz, A Abu-Horowitz… - Nucleic Acids …, 2015 - academic.oup.com
DNA origami is a robust method for the fabrication of nanoscale 2D and 3D objects with
complex features and geometries. The process of DNA origami folding has been recently studied…

[HTML][HTML] Hematologic biomarkers in childhood cataracts

O Wussuki-Lior, A Abu-Horowitz, I Netzer, Z Almer… - Molecular …, 2011 - ncbi.nlm.nih.gov
Purpose To date, more than thirty nine genetic loci have been associated with congenital
cataracts. Despite this progress, current diagnostic techniques are insufficient for unraveling …

Nanoscale robots exhibiting quorum sensing

Y Amir, A Abu-Horowitz, J Werfel, I Bachelet - Artificial Life, 2019 - direct.mit.edu
Multi-agent systems demonstrate the ability to collectively perform complex tasks (eg,
construction, search, and locomotion) with greater speed, efficiency, or effectiveness than could a …

Designing a bio-responsive robot from DNA origami

E Ben-Ishay, A Abu-Horowitz, I Bachelet - JoVE (Journal of Visualized …, 2013 - jove.com
Nucleic acids are astonishingly versatile. In addition to their natural role as storage medium
for biological information1, they can be utilized in parallel computing2,3 , recognize and bind …

A non-newtonian fluid robot

…, S Sasson, T Barkai, N Hadar, A Abu-Horowitz… - Artificial Life, 2016 - direct.mit.edu
New types of robots inspired by biological principles of assembly, locomotion, and behavior
have been recently described. In this work we explored the concept of robots that are based …