User profiles for A. Ashley-Koch
Allison Ashley-KochDuke University Medical Center Verified email at duke.edu Cited by 18809 |
The genetic architecture of the human cerebral cortex
…, M Andersson, T Ard, NJ Armstrong, A Ashley-Koch… - Science, 2020 - science.org
INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological, …
Variations in human cortical surface area and thickness are associated with neurological, …
[HTML][HTML] Genetic diversity fuels gene discovery for tobacco and alcohol use
Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of worldwide
deaths, respectively, due largely to broad increased risk for disease and injury 1 , 2 , 3 – …
deaths, respectively, due largely to broad increased risk for disease and injury 1 , 2 , 3 – …
[HTML][HTML] Largest GWAS of PTSD (N= 20 070) yields genetic overlap with schizophrenia and sex differences in heritability
…, LM Almli, AB Amstadter, AE Ashley-Koch… - Molecular …, 2018 - nature.com
The Psychiatric Genomics Consortium-Posttraumatic Stress Disorder group (PGC-PTSD)
combined genome-wide case–control molecular genetic data across 11 multiethnic studies to …
combined genome-wide case–control molecular genetic data across 11 multiethnic studies to …
[HTML][HTML] International meta-analysis of PTSD genome-wide association studies identifies sex-and ancestry-specific genetic risk loci
The risk of posttraumatic stress disorder (PTSD) following trauma is heritable, but robust
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD …
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD …
[PDF][PDF] Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism
…, MM Menold, ER Martin, AE Ashley-Koch… - The American Journal of …, 2005 - cell.com
… Finally, we used a multianalytic approach, as described elsewhere (Ashley-Koch et al.
2004), to interpret our findings. This approach looked for the convergence of results across …
2004), to interpret our findings. This approach looked for the convergence of results across …
Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease
…, MF Abdelmalek, ME Garrett, A Ashley–Koch… - Gastroenterology, 2013 - Elsevier
Background & Aims Cirrhosis and liver cancer are potential outcomes of advanced nonalcoholic
fatty liver disease (NAFLD). It is not clear what factors determine whether patients will …
fatty liver disease (NAFLD). It is not clear what factors determine whether patients will …
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus
Central corneal thickness (CCT) is associated with eye conditions including keratoconus and
glaucoma. We performed a meta-analysis on >20,000 individuals in European and Asian …
glaucoma. We performed a meta-analysis on >20,000 individuals in European and Asian …
Epidemiologic and genetic aspects of spina bifida and other neural tube defects
KS Au, A Ashley‐Koch… - Developmental disabilities …, 2010 - Wiley Online Library
The worldwide incidence of neural tube defects (NTDs) ranges from 1.0 to 10.0 per 1,000
births with almost equal frequencies between two major categories: anencephaly and spina …
births with almost equal frequencies between two major categories: anencephaly and spina …
Self-regulation of emotion, functional impairment, and comorbidity among childrenwith AD/HD
…, SH Kollins, A Ashley-Koch - Journal of attention …, 2011 - journals.sagepub.com
Objective: This study investigated the role of self-regulation of emotion in relation to functional
impairment and comorbidity among children with and without AD/HD. Method: A total of …
impairment and comorbidity among children with and without AD/HD. Method: A total of …
The psychencode project
…, A Amiri, C Armoskus, AE Ashley-Koch… - Nature …, 2015 - nature.com
Recent research on disparate psychiatric disorders has implicated rare variants in genes
involved in global gene regulation and chromatin modification, as well as many common …
involved in global gene regulation and chromatin modification, as well as many common …