Publisher Summary This chapter describes two types of purification methods for Cathepsin B,
Cathepsin H, and Cathepsin L. Method I is applicable to large amounts of frozen tissues, …

Salivary gland tumours are a relatively rare and morphologically diverse group of lesions.
Although most clinicians and pathologists will have encountered the more common benign …

The sequence of extreme September sea ice extent minima over the past decade suggests
acceleration in the response of the Arctic sea ice cover to external forcing, hastening the …

A system is described for building up serial sections into a three dimensional structure,
incorporating density, that can be displayed and then further manipulated by rotation about three …

BACKGROUND Cell-free fetal DNA (cffDNA) constitutes approximately 10% of the cell-free
DNA in maternal plasma and is a suitable source of fetal genetic material for noninvasive …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta-…

1. L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) at a concentration of 0.5
mM had no effect on the serine proteinases plasma kallikrein and leucocyte elastase or the …

Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …

The dimethylmethylene blue assay for sulphated glycosaminoglycans has found wide acceptance
as a quick and simple method of measuring the sulphated glycosaminoglycan content …

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic
outcomes, independent of overall adiposity. To increase our understanding of the genetic …