The hippocampal formation is a brain structure integrally involved in episodic memory, spatial
navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal …

Genome-wide association studies (GWASs) have identified hundreds of loci associated with
Crohn’s disease (CD). However, as with all complex diseases, robust identification of the …

Intracranial volume reflects the maximally attained brain size during development, and remains
stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain …

Pressure on agricultural land from a rising global population is necessitating the maximisation
of food production per unit area of cultivation. Attention is increasingly turning to Vertical …

Background— The burden of cerebral white matter hyperintensities (WMH) is associated
with an increased risk of stroke, dementia, and death. WMH are highly heritable, but their …

We assembled and analyzed genetic data of 47,351 multiple sclerosis (MS) subjects and
68,284 control subjects and establish a reference map of the genetic architecture of MS that …

Multiple sclerosis is a complex neurological disease, with ∼20% of risk heritability attributable
to common genetic variants, including >230 identified by genome-wide association …

Multiple sclerosis is a leading cause of neurological disability in adults. Heterogeneity in
multiple sclerosis clinical presentation has posed a major challenge for identifying genetic …

The aims of this study were: (i) to determine to what degree multiple sclerosis-associated
loci discovered in European populations also influence susceptibility in African Americans; (ii) …

The rules relating the sign of the n → π * Cotton effect to the absolute ring geometry in endo
αβ-unsaturated lactones are examined in the light of evidence from x-ray structure analyses. …