User profiles for A. Bruni‐Cardoso

Alexandre Bruni-Cardoso

Professor in Biochemistry and Molecular Biology- University of São Paulo
Verified email at iq.usp.br
Cited by 1520

Viral infection and smell loss: The case of COVID‐19

I Glezer, A BruniCardoso… - Journal of …, 2021 - Wiley Online Library
Olfactory disorders have been increasingly reported in individuals infected with SARS‐CoV‐2,
the virus causing the coronavirus disease 2019 (COVID‐19). Losing the sense of smell …

[HTML][HTML] Sleeping beauty and the microenvironment enchantment: microenvironmental regulation of the proliferation-quiescence decision in normal tissues and in …

…, PF Ribeiro, A Bruni-Cardoso - Frontiers in cell and …, 2018 - frontiersin.org
Cells from prokaryota to the more complex metazoans cease proliferating at some point in
their lives and enter a reversible, proliferative-dormant state termed quiescence. The …

Coherent angular motion in the establishment of multicellular architecture of glandular tissues

…, H Mori, R Mroue, A Bruni-Cardoso… - Proceedings of the …, 2012 - National Acad Sciences
Glandular tissues form ducts (tubes) and acini (spheres) in multicellular organisms. This
process is best demonstrated in the organization of the ductal tree of the mammary gland and in …

[HTML][HTML] Methylene blue photodynamic therapy induces selective and massive cell death in human breast cancer cells

…, VM Gomes, MF Mineiro, FC Meotti, A Bruni-Cardoso… - BMC cancer, 2017 - Springer
Background Breast cancer is the main cause of mortality among women. The disease
presents high recurrence mainly due to incomplete efficacy of primary treatment in killing all …

[HTML][HTML] Mitochondrial morphology regulates organellar Ca2+ uptake and changes cellular Ca2+ homeostasis

…, P Nolasco, FRM Laurindo, A BruniCardoso… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Abstract Changes in mitochondrial size and shape have been implicated in several physiologic
processes, but their role in mitochondrial Ca 2+ uptake regulation and overall cellular Ca …

[HTML][HTML] The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling

…, D Schechtman, FC Meotti, A Bruni-Cardoso… - Journal of Biological …, 2021 - ASBMB
SARS-CoV-2 nonstructural protein 3 (Nsp3) contains a macrodomain that is essential for
coronavirus pathogenesis and is thus an attractive target for drug development. This …

[PDF][PDF] Laminin-111 and the level of nuclear actin regulate epithelial quiescence via exportin-6

…, H Mori, HF Carvalho, MJ Bissell, A Bruni-Cardoso - Cell reports, 2017 - cell.com
Nuclear actin (N-actin) is known to participate in the regulation of gene expression. We
showed previously that N-actin levels mediate the growth and quiescence of mouse epithelial …

Deep nuclear invaginations are linked to cytoskeletal filaments–integrated bioimaging of epithelial cells in 3D culture

…, WT Tsai, H Huang, A Bruni-Cardoso… - Journal of cell …, 2017 - journals.biologists.com
The importance of context in regulation of gene expression is now an accepted principle;
yet the mechanism by which the microenvironment communicates with the nucleus and …

[HTML][HTML] Distinct photo-oxidation-induced cell death pathways lead to selective killing of human breast cancer cells

…, DRQ de Almeida, VM Gomes, A Bruni-Cardoso… - Cell death & …, 2020 - nature.com
Lack of effective treatments for aggressive breast cancer is still a major global health
problem. We have previously reported that photodynamic therapy using methylene blue as …

Osteoclast-derived matrix metalloproteinase-9 directly affects angiogenesis in the prostate tumor–bone microenvironment

A Bruni-Cardoso, LC Johnson, RL Vessella… - Molecular Cancer …, 2010 - AACR
In human prostate to bone metastases and in a novel rodent model that recapitulates
prostate tumor–induced osteolytic and osteogenic responses, we found that osteoclasts are a …