Fiji: an open-source platform for biological-image analysis
Fiji is a distribution of the popular open-source software ImageJ focused on biological-image
analysis. Fiji uses modern software engineering practices to combine powerful software …
analysis. Fiji uses modern software engineering practices to combine powerful software …
The myeloid cells of the central nervous system parenchyma
RM Ransohoff, AE Cardona - Nature, 2010 - nature.com
A microglial cell is both a glial cell of the central nervous system and a mononuclear
phagocyte, which belongs to the haematopoietic system and is involved in inflammatory and …
phagocyte, which belongs to the haematopoietic system and is involved in inflammatory and …
Human recombinant activated protein C for severe sepsis
…, AF Cardona, AF Cardona‐Zorrilla - Cochrane database …, 2007 - cochranelibrary.com
Background Sepsis is a common, expensive and frequently fatal condition. There is an urgent
need for developing new therapies to further reduce severe sepsis‐induced mortality. One …
need for developing new therapies to further reduce severe sepsis‐induced mortality. One …
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
J Viala, C Chaput, IG Boneca, A Cardona… - Nature …, 2004 - nature.com
Epithelial cells can respond to conserved bacterial products that are internalized after either
bacterial invasion or liposome treatment of cells. We report here that the noninvasive Gram-…
bacterial invasion or liposome treatment of cells. We report here that the noninvasive Gram-…
Control of microglial neurotoxicity by the fractalkine receptor
AE Cardona, EP Pioro, ME Sasse, V Kostenko… - Nature …, 2006 - nature.com
Microglia, the resident inflammatory cells of the CNS, are the only CNS cells that express the
fractalkine receptor (CX3CR1). Using three different in vivo models, we show that CX3CR1 …
fractalkine receptor (CX3CR1). Using three different in vivo models, we show that CX3CR1 …
Middle Miocene closure of the Central American seaway
Uranium-lead geochronology in detrital zircons and provenance analyses in eight boreholes
and two surface stratigraphic sections in the northern Andes provide insight into the time of …
and two surface stratigraphic sections in the northern Andes provide insight into the time of …
Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a …
…, L Bolotina, M Botha, S Buddu, C Caglevic, A Cardona… - The Lancet, 2019 - thelancet.com
Background First-line pembrolizumab monotherapy improves overall and progression-free
survival in patients with untreated metastatic non-small-cell lung cancer with a programmed …
survival in patients with untreated metastatic non-small-cell lung cancer with a programmed …
[HTML][HTML] TrakEM2 software for neural circuit reconstruction
A key challenge in neuroscience is the expeditious reconstruction of neuronal circuits. For
model systems such as Drosophila and C. elegans, the limiting step is no longer the …
model systems such as Drosophila and C. elegans, the limiting step is no longer the …
The connectome of an insect brain
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats
…, M Jaglin, A Bruneau, S Vancassel, A Cardona… - …, 2014 - Elsevier
Background and aims Establishment of the gut microbiota is one of the most important events
in early life and emerging evidence indicates that the gut microbiota influences several …
in early life and emerging evidence indicates that the gut microbiota influences several …