System analysis shows distinct mechanisms and common principles of nuclear envelope protein dynamics

N Zuleger, DA Kelly, AC Richardson, ARW Kerr… - Journal of Cell …, 2011 - rupress.org
The nuclear envelope contains >100 transmembrane proteins that continuously exchange
with the endoplasmic reticulum and move within the nuclear membranes. To better …

[PDF][PDF] A superfamily of actin-binding proteins at the actin-membrane nexus of higher plants

…, EKS Ingle, TJ Hawkins, S Chapman, AC Richardson… - Current Biology, 2012 - cell.com
Complex animals use a wide variety of adaptor proteins to produce specialized sites of
interaction between actin and membranes. Plants do not have these protein families, yet actin-…

[HTML][HTML] NET4 and RabG3 link actin to the tonoplast and facilitate cytoskeletal remodelling during stomatal immunity

…, JTM Kroon, MT Bui, AC Richardson… - Nature …, 2023 - nature.com
Members of the NETWORKED (NET) family are involved in actin-membrane interactions.
Here we show that two members of the NET family, NET4A and NET4B, are essential for …

[PDF][PDF] STING nuclear partners contribute to innate immune signaling responses

…, F de Lima Alves, M Tingey, E Gaunt, AC Richardson… - Iscience, 2021 - cell.com
STimulator of INterferon Genes (STING) is an adaptor for cytoplasmic DNA sensing by
cGAMP/cGAS that helps trigger innate immune responses (IIRs). Although STING is mostly …

Modular nanometer-scale structuring of gel fibres by sequential self-organization

L Applegarth, N Clark, AC Richardson… - Chemical …, 2005 - pubs.rsc.org
Ag (I) and Cu (II) complexes of a series of simple bis (urea) ligands form soft metallogels. X-
ray crystallographic results suggests that the gels' structure is based on hydrogen bonding to …

Diagnosis and relation to general health of shoulder disorders presenting to primary care

AJK Ostor, CA Richards, AT Prevost, CA Speed… - …, 2005 - academic.oup.com
Objectives. To prospectively evaluate the incidence, spectrum of disease and relation to
general health of shoulder disorders in primary care. Methods. Patients presenting with …

Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells

DM Weinstock, CA Richardson, B Elliott, M Jasin - DNA repair, 2006 - Elsevier
Reciprocal chromosomal translocations are implicated in the etiology of many tumors,
including leukemias, lymphomas, and sarcomas. DNA double-strand breaks (DSBs) caused by …

A question of access: an exploration of the factors that influence the health of young males aged 15 to 19 living in Corby and their use of health care services

CA Richardson, F Rabiee - Health education journal, 2001 - journals.sagepub.com
Objective To explore the factors that influence young men's access to health services with a
view to identifying the potential for health promotion interventions in this area. Design A …

TWEAK is an endothelial cell growth and chemotactic factor that also potentiates FGF-2 and VEGF-A mitogenic activity

PJ Donohue, CM Richards, SAN Brown… - … , and vascular biology, 2003 - Am Heart Assoc
Objective— TWEAK, a member of the tumor necrosis factor superfamily, binds to the Fn14
receptor and stimulates angiogenesis in vivo. In this study, we investigated Fn14 gene …

A possible linkage between AMP‐activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway

N Kimura, C Tokunaga, S Dalal, C Richardson… - Genes to …, 2003 - Wiley Online Library
Background: The mammalian target of rapamycin (mTOR) regulates multiple cellular
functions including translation in response to nutrients, especially amino acids. AMP‐activated …