The transmission of a complete set of chromosomes to daughter cells during cell division is
vital for development and tissue homeostasis. The spindle assembly checkpoint (SAC) …

… De Wulf, AD McAinsh & PK Sorger, submitted). The biochemical activities of the Mtw1 complex,
such as MT binding, have not been determined and we therefore classify the complex as …

Kinetochores are molecular machines that power chromosome segregation during the
mitotic and meiotic cell divisions of all eukaryotes. Aristotle explains how we think we have …

… However, even these kinetochores consist of at least 65 different protein subunits (McAinsh
et … This article must therefore be hereby marked “advertisement” in accordance with 18 USC …

… (AD McAinsh et al., submitted). Importantly, for the purposes of the current analysis, the
identification of new human kinetochore proteins means that one or more subunits are present in …

… Meraldi, and AD McAinsh conceived and initiated this study. AC Amaro established the …
Meraldi, and AD McAinsh wrote the manuscript with help from EM King, AC Amaro, JF Dorn, …

Chromosome segregation in metazoans requires the alignment of sister kinetochores on
the metaphase plate. During chromosome alignment, bioriented kinetochores move …

… McAinsh; Kinetochore-generated pushing forces separate centrosomes during bipolar
spindle assembly. J Cell Biol 9 February 2009; 184 (3): 365–372. doi: https://doi.org/10.1083/jcb.…

Background Kinetochores are large multiprotein complexes indispensable for proper
chromosome segregation. Although Drosophila is a classical model organism for studies of …

The dynamic organization of microtubules into parallel arrays allows interphase cells to set
up multi-lane highways for intracellular transport and M-phase cells to build the mitotic and …