[HTML][HTML] Methylation plotter: a web tool for dynamic visualization of DNA methylation data
I Mallona, A Díez-Villanueva, MA Peinado - Source code for biology and …, 2014 - Springer
Methylation plotter is a Web tool that allows the visualization of methylation data in a user-friendly
manner and with publication-ready quality. The user is asked to introduce a file …
manner and with publication-ready quality. The user is asked to introduce a file …
regioneR: an R/Bioconductor package for the association analysis of genomic regions based on permutation tests
Motivation: Statistically assessing the relation between a set of genomic regions and other
genomic features is a common challenging task in genomic and epigenomic analyses. …
genomic features is a common challenging task in genomic and epigenomic analyses. …
[HTML][HTML] Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer
A Díez-Villanueva, I Mallona, MA Peinado - Epigenetics & chromatin, 2015 - Springer
Background The Cancer Genome Atlas (TCGA) offers a multilayered view of genomics and
epigenomics data of many human cancer types. However, the retrieval of expression and …
epigenomics data of many human cancer types. However, the retrieval of expression and …
Low adherence to the western and high adherence to the mediterranean dietary patterns could prevent colorectal cancer
…, T Fernández-Villa, A Díez-Villanueva… - European journal of …, 2019 - Springer
Purpose To assess if the associations found between three previously identified dietary
patterns with breast, prostate and gastric cancer are also observed for colorectal cancer (CRC). …
patterns with breast, prostate and gastric cancer are also observed for colorectal cancer (CRC). …
[HTML][HTML] Risk model for colorectal cancer in Spanish population using environmental and genetic factors: results from the MCC-Spain study
G Ibáñez-Sanz, A Díez-Villanueva, MH Alonso… - Scientific reports, 2017 - nature.com
Colorectal cancer (CRC) screening of the average risk population is only indicated
according to age. We aim to elaborate a model to stratify the risk of CRC by incorporating …
according to age. We aim to elaborate a model to stratify the risk of CRC by incorporating …
The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells
Cancer cells exhibit multiple epigenetic changes with prominent local DNA hypermethylation
and widespread hypomethylation affecting large chromosomal domains. Epigenome …
and widespread hypomethylation affecting large chromosomal domains. Epigenome …
Deconstruction of DNA methylation patterns during myogenesis reveals specific epigenetic events in the establishment of the skeletal muscle lineage
The progressive restriction of differentiation potential from pluripotent embryonic stem cells (ESCs)
to tissue‐specific stem cells involves widespread epigenetic reprogramming, …
to tissue‐specific stem cells involves widespread epigenetic reprogramming, …
[HTML][HTML] Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer
I Cebola, J Custodio, M Muñoz, A Díez-Villanueva… - Clinical …, 2015 - Springer
Background Misregulation of the PTGS (prostaglandin endoperoxide synthase, also known
as cyclooxygenase or COX) pathway may lead to the accumulation of pro-inflammatory …
as cyclooxygenase or COX) pathway may lead to the accumulation of pro-inflammatory …
[HTML][HTML] Genetic effects on transcriptome profiles in colon epithelium provide functional insights for genetic risk loci
…, M Devall, SJ Plummer, A Díez-Villanueva… - Cellular and molecular …, 2021 - Elsevier
Background & Aims The association of genetic variation with tissue-specific gene expression
and alternative splicing guides functional characterization of complex trait-associated loci …
and alternative splicing guides functional characterization of complex trait-associated loci …
Transcriptome-wide association study for inflammatory bowel disease reveals novel candidate susceptibility genes in specific colon subsites and tissue categories
…, M Obón-Santacana, A Díez-Villanueva… - Journal of Crohn's …, 2022 - academic.oup.com
Background and Aims Genome-wide association studies [GWAS] for inflammatory bowel
disease [IBD] have identified 240 risk variants. However, the benefit of understanding the …
disease [IBD] have identified 240 risk variants. However, the benefit of understanding the …