[HTML][HTML] Methylation plotter: a web tool for dynamic visualization of DNA methylation data

I Mallona, A Díez-Villanueva, MA Peinado - Source code for biology and …, 2014 - Springer
Methylation plotter is a Web tool that allows the visualization of methylation data in a user-friendly
manner and with publication-ready quality. The user is asked to introduce a file …

regioneR: an R/Bioconductor package for the association analysis of genomic regions based on permutation tests

B Gel, A Díez-Villanueva, E Serra, M Buschbeck… - …, 2016 - academic.oup.com
Motivation: Statistically assessing the relation between a set of genomic regions and other
genomic features is a common challenging task in genomic and epigenomic analyses. …

[HTML][HTML] Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer

A Díez-Villanueva, I Mallona, MA Peinado - Epigenetics & chromatin, 2015 - Springer
Background The Cancer Genome Atlas (TCGA) offers a multilayered view of genomics and
epigenomics data of many human cancer types. However, the retrieval of expression and …

Low adherence to the western and high adherence to the mediterranean dietary patterns could prevent colorectal cancer

…, T Fernández-Villa, A Díez-Villanueva… - European journal of …, 2019 - Springer
Purpose To assess if the associations found between three previously identified dietary
patterns with breast, prostate and gastric cancer are also observed for colorectal cancer (CRC). …

[HTML][HTML] Risk model for colorectal cancer in Spanish population using environmental and genetic factors: results from the MCC-Spain study

G Ibáñez-Sanz, A Díez-Villanueva, MH Alonso… - Scientific reports, 2017 - nature.com
Colorectal cancer (CRC) screening of the average risk population is only indicated
according to age. We aim to elaborate a model to stratify the risk of CRC by incorporating …

The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells

M Jordà, A Díez-Villanueva, I Mallona… - Genome …, 2017 - genome.cshlp.org
Cancer cells exhibit multiple epigenetic changes with prominent local DNA hypermethylation
and widespread hypomethylation affecting large chromosomal domains. Epigenome …

Deconstruction of DNA methylation patterns during myogenesis reveals specific epigenetic events in the establishment of the skeletal muscle lineage

E Carrio, A DíezVillanueva, S Lois, I Mallona… - Stem Cells, 2015 - academic.oup.com
The progressive restriction of differentiation potential from pluripotent embryonic stem cells (ESCs)
to tissue‐specific stem cells involves widespread epigenetic reprogramming, …

[HTML][HTML] Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer

I Cebola, J Custodio, M Muñoz, A Díez-Villanueva… - Clinical …, 2015 - Springer
Background Misregulation of the PTGS (prostaglandin endoperoxide synthase, also known
as cyclooxygenase or COX) pathway may lead to the accumulation of pro-inflammatory …

[HTML][HTML] Genetic effects on transcriptome profiles in colon epithelium provide functional insights for genetic risk loci

…, M Devall, SJ Plummer, A Díez-Villanueva… - Cellular and molecular …, 2021 - Elsevier
Background & Aims The association of genetic variation with tissue-specific gene expression
and alternative splicing guides functional characterization of complex trait-associated loci …

Transcriptome-wide association study for inflammatory bowel disease reveals novel candidate susceptibility genes in specific colon subsites and tissue categories

…, M Obón-Santacana, A Díez-Villanueva… - Journal of Crohn's …, 2022 - academic.oup.com
Background and Aims Genome-wide association studies [GWAS] for inflammatory bowel
disease [IBD] have identified 240 risk variants. However, the benefit of understanding the …