Mapping of large sets of high‐throughput sequencing reads to a reference genome is one
of the foundational steps in RNA‐seq data analysis. The STAR software package performs …

Eukaryotic cells make many types of primary and processed RNAs that are found either in
specific subcellular compartments or throughout the cells. A complete catalogue of these …

Motivation: Accurate alignment of high-throughput RNA-seq data is a challenging and yet
unsolved problem because of the non-contiguous transcript structure, relatively short read …

The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate these …

Drosophila melanogaster is one of the most well studied genetic model organisms; nonetheless,
its genome still contains unannotated coding and non-coding genes, transcripts, exons …

The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally
conserved across mammals 1 . Here, using high-throughput transcriptomic and epigenomic …

To gain insight into how genomic information is translated into cellular and developmental
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …

Although the similarities between humans and mice are typically highlighted, morphologically
and genetically, there are many differences. To better understand these two species on a …

To complement the human Encyclopedia of DNA Elements (ENCODE) project and to enable
a broad range of mouse genomics efforts, the Mouse ENCODE Consortium is applying the …

Background Accurate fusion transcript detection is essential for comprehensive characterization
of cancer transcriptomes. Over the last decade, multiple bioinformatic tools have been …