[HTML][HTML] Glioblastoma remodelling of human neural circuits decreases survival

…, C Nava Gonzales, R Sudharshan, A Egladyous… - Nature, 2023 - nature.com
Gliomas synaptically integrate into neural circuits 1 , 2 . Previous research has demonstrated
bidirectional interactions between neurons and glioma cells, with neuronal activity driving …

Interactive effects of molecular, therapeutic, and patient factors on outcome of diffuse low-grade glioma

…, S Kakaizada, A Egladyous… - Journal of Clinical …, 2023 - ingentaconnect.com
PURPOSE In patients with diffuse low-grade glioma (LGG), the extent of surgical tumor resection
(EOR) has a controversial role, in part because a randomized clinical trial with different …

Complementary networks of cortical somatostatin interneurons enforce layer specific control

…, D Risso, D Stafford, B Snyder, A Egladyous… - Elife, 2019 - elifesciences.org
10.7554/eLife.43696.001 The neocortex is functionally organized into layers. Layer four
receives the densest bottom up sensory inputs, while layers 2/3 and 5 receive top down inputs …

Glioblastoma remodeling of neural circuits in the human brain decreases survival

…, A Lee, A Aabedi, C Cao, R Sudharshan, A Egladyous… - BioRxiv, 2021 - biorxiv.org
Gliomas synaptically integrate into neural circuits. Prior work has demonstrated bidirectional
interactions between neurons and glioma cells, with neuronal activity driving glioma growth …

Tribute to William Edward Hunt and Robert McDonald Hess Jr.: pioneers in the clinical classification of ruptured intracranial aneurysms

AS Liang, A Egladyous, F Jumah, B Raju, A Nagaraj… - World Neurosurgery, 2022 - Elsevier
William Edward Hunt (1921–1999) and Robert McDonald Hess Jr. (1931–2019) were
pioneers in revolutionizing the early surgical management of ruptured intracranial aneurysms. …

Shunt treatment for coccidioidomycosis-related hydrocephalus: a single-center series

RA Morshed, AT Lee, A Egladyous, LN Avalos… - World Neurosurgery, 2020 - Elsevier
Objective Coccidioidomycosis is a fungal infection endemic to the southwestern United
States. Hydrocephalus can develop after intracranial dissemination, and management of this …

[HTML][HTML] Neuro-Oncology Patients as Human Research Subjects: Ethical Considerations for Cognitive and Behavioral Testing for Research Purposes

J Kaur, A Egladyous, C Valdivia, AGS Daniel… - Cancers, 2022 - mdpi.com
Simple Summary Previous publications have elaborated on the exposure of ethical issues
surrounding the enrollment and neurological testing of brain cancer patients into clinical …

Complementary subnetworks of cortical somatostatin interneurons

A Naka, B Shababo, B Snyder, AY Egladyous… - bioRxiv, 2018 - biorxiv.org
The connectivity patterns of excitatory and inhibitory microcircuits are fundamental to computation
in the neocortex. Highly specific excitatory projections form a stereotyped microcircuit …

Coccidioidal meningitis and brain abscesses: analysis of 71 cases at a referral center

KW Drake, RD Adam - Neurology, 2009 - AAN Enterprises
Objective: Coccidioides species are the most common etiologic agents of chronic meningitis
in regions endemic for coccidioidomycosis. Occasionally, even short-term travel to endemic …

Controversies in the management of central nervous system coccidioidomycosis

GR Thompson III, NM Ampel, JE Blair… - Clinical Infectious …, 2022 - academic.oup.com
Central nervous system infection with Coccidioides spp. is fatal if untreated and complications
occur even when therapy is directed by experienced clinicians. We convened a panel of …