DNA compaction: fundamentals and applications

A Estévez-Torres, D Baigl - Soft Matter, 2011 - pubs.rsc.org
Compaction is the process in which a large DNA molecule undergoes a transition between
an elongated conformation and a very compact form. In nature, DNA compaction occurs to …

Spatial waves in synthetic biochemical networks

A Padirac, T Fujii, A Estévez-Torres… - Journal of the American …, 2013 - ACS Publications
We report the experimental observation of traveling concentration waves and spirals in a
chemical reaction network built from the bottom up. The mechanism of the network is an …

Microscopic agents programmed by DNA circuits

…, AS Zadorin, JC Galas, T Fujii, A Estevez-Torres… - Nature …, 2017 - nature.com
Abstract Information stored in synthetic nucleic acids sequences can be used in vitro to create
complex reaction networks with precisely programmed chemical dynamics. Here, we scale …

Quadruplex-based molecular beacons as tunable DNA probes

A Bourdoncle, A Estevez Torres, C Gosse… - Journal of the …, 2006 - ACS Publications
Molecular beacons (MBs) are fluorescent nucleic acid probes with a hairpin-shaped structure
in which the 5‘ and 3‘ ends are self-complementary. Due to a change in their emissive …

Synthesis of programmable reaction-diffusion fronts using DNA catalyzers

AS Zadorin, Y Rondelez, JC Galas, A Estevez-Torres - Physical review letters, 2015 - APS
We introduce a DNA-based reaction-diffusion (RD) system in which reaction and diffusion
terms can be precisely and independently controlled. The effective diffusion coefficient of an …

Synthesis and materialization of a reaction–diffusion French flag pattern

…, G Urtel, A Zambrano, JC Galas, A Estevez-Torres - Nature …, 2017 - nature.com
During embryo development, patterns of protein concentration appear in response to morphogen
gradients. These patterns provide spatial and chemical information that directs the fate …

Sequence-independent and reversible photocontrol of transcription/expression systems using a photosensitive nucleic acid binder

A Estévez-Torres, C Crozatier… - Proceedings of the …, 2009 - National Acad Sciences
To understand non-trivial biological functions, it is crucial to develop minimal synthetic
models that capture their basic features. Here, we demonstrate a sequence-independent, …

Tunable corrugated patterns in an active nematic sheet

…, JC Galas, A Maitra, A Estevez-Torres - Proceedings of the …, 2019 - National Acad Sciences
Active matter locally converts chemical energy into mechanical work and, for this reason, it
provides new mechanisms of pattern formation. In particular, active nematic fluids made of …

High-throughput and long-term observation of compartmentalized biochemical oscillators

…, M Leocmach, AJ Genot, A Estévez-Torres… - Chemical …, 2013 - pubs.rsc.org
We report the splitting of an oscillating DNA circuit into ∼700 droplets with picoliter volumes.
Upon incubation at constant temperature, the droplets display sustained oscillations that …

Observing and controlling the folding pathway of DNA origami at the nanoscale

…, C David, S Rudiuk, D Baigl, A Estevez-Torres - ACS …, 2016 - ACS Publications
DNA origami is a powerful method to fold DNA into rationally designed nanostructures that
holds great promise for bionanotechnology. However, the folding mechanism has yet to be …