User profiles for A. Fasano

Alessio Fasano

Professor of Pediatrics MGH Harvard Medical School - Professor of Nutrition Harvard TH …
Verified email at mgh.harvard.edu
Cited by 66172

[HTML][HTML] Chronic inflammation in the etiology of disease across the life span

…, C Franceschi, L Ferrucci, DW Gilroy, A Fasano… - Nature medicine, 2019 - nature.com
Although intermittent increases in inflammation are critical for survival during physical injury
and infection, recent research has revealed that certain social, environmental and lifestyle …

Current approaches to diagnosis and treatment of celiac disease: an evolving spectrum

A Fasano, C Catassi - Gastroenterology, 2001 - Elsevier
Celiac disease (CD) is a syndrome characterized by damage of the small intestinal mucosa
caused by the gliadin fraction of wheat gluten and similar alcohol-soluble proteins (…

[HTML][HTML] Spectrum of gluten-related disorders: consensus on new nomenclature and classification

…, R Ullrich, D Villalta, U Volta, C Catassi, A Fasano - BMC medicine, 2012 - Springer
A decade ago celiac disease was considered extremely rare outside Europe and, therefore,
was almost completely ignored by health care professionals. In only 10 years, key …

The Oslo definitions for coeliac disease and related terms

JF Ludvigsson, DA Leffler, JC Bai, F Biagi, A Fasano… - Gut, 2013 - gut.bmj.com
Objective The literature suggests a lack of consensus on the use of terms related to coeliac
disease (CD) and gluten. Design A multidisciplinary task force of 16 physicians from seven …

[HTML][HTML] Microbiota transfer therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

…, JB Adams, AC Gregory, T Borody, L Chittick, A Fasano… - Microbiome, 2017 - Springer
Background Autism spectrum disorders (ASD) are complex neurobiological disorders that
impair social interactions and communication and lead to restricted, repetitive, and …

Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology …

…, GS Liptak, RB Colletti, A Fasano… - Journal of pediatric …, 2005 - journals.lww.com
Celiac disease is an immune-mediated enteropathy caused by a permanent sensitivity to
gluten in genetically susceptible individuals. It occurs in children and adolescents with …

Celiac disease

A Fasano, C Catassi - New England Journal of Medicine, 2012 - Mass Medical Soc
Key Clinical Points Celiac Disease Once considered a gastrointestinal disorder that mainly
affects white children, celiac disease is now known to affect persons of different ages, races, …

Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3

…, S Netzel–Arnett, T Antalis, SN Vogel, A Fasano - Gastroenterology, 2008 - Elsevier
Background & Aims: Celiac disease is an immune-mediated enteropathy triggered by gliadin,
a component of the grain protein gluten. Gliadin induces an MyD88-dependent zonulin …

Pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): clinical presentation, infectivity, and immune responses

…, D Irimia, AG Edlow, G Alter, JZ Li, A Fasano - The Journal of …, 2020 - Elsevier
Objectives As schools plan for re-opening, understanding the potential role children play in
the coronavirus infectious disease 2019 (COVID-19) pandemic and the factors that drive …

[HTML][HTML] Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4

…, JC Fleet, S Kortagere, P Mukherjee, A Fasano… - Immunity, 2014 - cell.com
Intestinal microbial metabolites are conjectured to affect mucosal integrity through an
incompletely characterized mechanism. Here we showed that microbial-specific indoles regulated …