User profiles for A. Friedrich

Prof. Dr. Alex W. Friedrich

University of Groningen, University Hospital Groningen, The Netherlands
Verified email at umcg.nl
Cited by 28668

[HTML][HTML] The molecular evolution of methicillin-resistant Staphylococcus aureus

RH Deurenberg, C Vink, S Kalenic, AW Friedrich… - Clinical Microbiology …, 2007 - Elsevier
Staphylococcus aureus is a potentially pathogenic bacterium that causes a broad spectrum
of diseases. S. aureus can adapt rapidly to the selective pressure of antibiotics, and this has …

Meticillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods

S Stefani, DR Chung, JA Lindsay, AW Friedrich… - International journal of …, 2012 - Elsevier
This article reviews recent findings on the global epidemiology of healthcare-acquired/associated
(HA), community-acquired/associated (CA) and livestock-associated (LA) meticillin-…

Overview of molecular typing methods for outbreak detection and epidemiological surveillance

…, F Laurent, H Grundmann, AW Friedrich… - …, 2013 - eurosurveillance.org
Typing methods for discriminating different bacterial isolates of the same species are
essential epidemiological tools in infection prevention and control. Traditional typing systems …

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

…, G Cornaglia, OJ Dyar, AW Friedrich… - The Lancet infectious …, 2018 - thelancet.com
Background The spread of antibiotic-resistant bacteria poses a substantial threat to morbidity
and mortality worldwide. Due to its large public health and societal implications, multidrug-…

[HTML][HTML] Genome evolution across 1,011 Saccharomyces cerevisiae isolates

J Peter, M De Chiara, A Friedrich, JX Yue, D Pflieger… - Nature, 2018 - nature.com
Large-scale population genomic surveys are essential to explore the phenotypic diversity of
natural populations. Here we report the whole-genome sequencing and phenotyping of …

Escherichia coli Harboring Shiga Toxin 2 Gene Variants: Frequency and Association with Clinical Symptoms

AW Friedrich, M Bielaszewska… - The Journal of …, 2002 - academic.oup.com
Shiga toxin (Stx)–producing Escherichia coli (STEC) from patients with hemolytic-uremic
syndrome (HUS), patients with diarrhea without HUS, or asymptomatic subjects were …

Methicillin-resistant Staphylococcus aureus (MRSA): burden of disease and control challenges in Europe

…, A Navarro Torné, W Witte, AW Friedrich - …, 2010 - eurosurveillance.org
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of healthcare- and
community-associated infections worldwide. Within the healthcare setting alone, MRSA …

Na+-d-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

…, V Vallon, H Kipp, A Jaschke, D Klessen, A Friedrich… - Diabetes, 2012 - Am Diabetes Assoc
To clarify the physiological role of Na + -d-glucose cotransporter SGLT1 in small intestine and
kidney, Sglt1 −/− mice were generated and characterized phenotypically. After gavage of d…

The G Protein–Gated Potassium Current IK,ACh Is Constitutively Active in Patients With Chronic Atrial Fibrillation

D Dobrev, A Friedrich, N Voigt, N Jost, E Wettwer… - Circulation, 2005 - Am Heart Assoc
Background— The molecular mechanism of increased background inward rectifier current (I
K1 ) in atrial fibrillation (AF) is not fully understood. We tested whether constitutively active …

[HTML][HTML] Application of next generation sequencing in clinical microbiology and infection prevention

…, S Rosema, ACM Veloo, K Zhou, AW Friedrich… - Journal of …, 2017 - Elsevier
Current molecular diagnostics of human pathogens provide limited information that is often
not sufficient for outbreak and transmission investigation. Next generation sequencing (NGS) …