Brown fat generates heat via the mitochondrial uncoupling protein UCP1, defending against
hypothermia and obesity. Recent data suggest that there are two distinct types of brown fat: …

The master transcription factor Pparγ regulates the general differentiation program of both
brown and white adipocytes. However, it has been unclear whether Pparγ also controls fat …

Osteosarcoma is a devastating tumor of bone, primarily affecting adolescents. Osteosarcoma
tumors are notoriously radioresistant. Radioresistant cancers, including osteosarcoma, …

Almost four decades of climate science have not yet led to transformative policy change at
the pace and scale required to confront the climate crisis. Colleagues in the planetary health …

Given the serious adverse health effects associated with many pollutants, and the inequitable
distribution of these effects between socioeconomic groups, air pollution is often a focus of …

Metabolic reprogramming in cancer is manifested by persistent aerobic glycolysis and
suppression of mitochondrial function and is known as the Warburg effect. The Warburg effect …

Objectives Although the therapeutic effects of horticulture on older adults have been widely
investigated, a recent and comprehensive synthesis of available evidence on outcomes is …

Mercury pollution poses risks for both human and ecosystem health. As a consequence,
controlling mercury pollution has become a policy goal on both global and national scales. We …

Although cyclophilin A (CypA) has been reported to be over-expressed in cancer cells and
solid tumors, its expression and role in glioblastomas have not been studied. Herein, we …

We explore implications of the United Nations Minamata Convention on Mercury for emissions
from Asian coal-fired power generation, and resulting changes to deposition worldwide …