Immune checkpoint inhibitors have emerged as a pillar in the management of advanced
malignancies. However, nonspecific immune activation may lead to immune-related adverse …

Abstract Treatment of postoperative pain should rely on results from randomized controlled
trials and meta-analyses of high scientific quality. The efficacy of a particular intervention may …

UNICORE is a European Grid Technology with more than 10 years of history. Originating
from the Supercomputing domain, the latest version UNICORE 6 has turned into a general-…

Study objective Although the World Health Organization recommends take-home naloxone
to address the increasing global burden of opioid-related deaths, few emergency …

Non‐invasive, biomedical devices have the potential to provide important, quantitative data
for the assessment of skin diseases and wound healing. Traditional methods either rely on …

Background Immune checkpoint inhibitors (ICIs) demonstrate unprecedented efficacy in
multiple malignancies; however, the mechanisms of sensitivity and resistance are poorly …

In recent years energy-aware computing has become a major topic, not only in wireless and
mobile devices but also in devices using wired technology. The ICT industry is consuming …

Adeno-associated virus (AAV) vectors with capsids of AAV serotype 9 enable an efficient
transduction of the heart upon intravenous injection of adult mice but also transduce the liver. …

Squamous cell carcinoma of the head and neck (SCCHN) is a group of cancers of epithelial
origin that may provide an ideal model for the study of gene-environment interaction. …

Background Giant cell arteritis (GCA) is a systemic vasculitis that preferentially targets
medium-sized and large arteries. The etiopathogenesis of the syndrome is not known, and …