Bayesian parameter inference for stochastic biochemical network models using particle Markov chain Monte Carlo
A Golightly, DJ Wilkinson - Interface focus, 2011 - royalsocietypublishing.org
Computational systems biology is concerned with the development of detailed mechanistic
models of biological processes. Such models are often stochastic and analytically intractable, …
models of biological processes. Such models are often stochastic and analytically intractable, …
Bayesian inference for nonlinear multivariate diffusion models observed with error
A Golightly, DJ Wilkinson - Computational Statistics & Data Analysis, 2008 - Elsevier
Diffusion processes governed by stochastic differential equations (SDEs) are a well-established
tool for modelling continuous time data from a wide range of areas. Consequently, …
tool for modelling continuous time data from a wide range of areas. Consequently, …
Bayesian sequential inference for nonlinear multivariate diffusions
A Golightly, DJ Wilkinson - Statistics and Computing, 2006 - Springer
In this paper, we adapt recently developed simulation-based sequential algorithms to the
problem concerning the Bayesian analysis of discretely observed diffusion processes. The …
problem concerning the Bayesian analysis of discretely observed diffusion processes. The …
Bayesian inference for stochastic kinetic models using a diffusion approximation
A Golightly, DJ Wilkinson - Biometrics, 2005 - academic.oup.com
This article is concerned with the Bayesian estimation of stochastic rate constants in the
context of dynamic models of intracellular processes. The underlying discrete stochastic kinetic …
context of dynamic models of intracellular processes. The underlying discrete stochastic kinetic …
Bayesian sequential inference for stochastic kinetic biochemical network models
A Golightly, DJ Wilkinson - Journal of Computational Biology, 2006 - liebertpub.com
As postgenomic biology becomes more predictive, the ability to infer rate parameters of genetic
and biochemical networks will become increasingly important. In this paper, we explore …
and biochemical networks will become increasingly important. In this paper, we explore …
Delayed acceptance particle MCMC for exact inference in stochastic kinetic models
Recently-proposed particle MCMC methods provide a flexible way of performing Bayesian
inference for parameters governing stochastic kinetic models defined as Markov (jump) …
inference for parameters governing stochastic kinetic models defined as Markov (jump) …
Black-box variational inference for stochastic differential equations
Parameter inference for stochastic differential equations is challenging due to the presence
of a latent diffusion process. Working with an Euler-Maruyama discretisation for the diffusion, …
of a latent diffusion process. Working with an Euler-Maruyama discretisation for the diffusion, …
Adaptive, delayed-acceptance MCMC for targets with expensive likelihoods
C Sherlock, A Golightly… - Journal of Computational …, 2017 - Taylor & Francis
When conducting Bayesian inference, delayed-acceptance (DA) Metropolis–Hastings (MH)
algorithms and DA pseudo-marginal MH algorithms can be applied when it is …
algorithms and DA pseudo-marginal MH algorithms can be applied when it is …
Problem-based learning to foster deep learning in preservice geography teacher education
A Golightly, S Raath - Journal of Geography, 2015 - Taylor & Francis
In South Africa, geography education students’ approach to deep learning has received little
attention. Therefore the purpose of this one-shot experimental case study was to evaluate …
attention. Therefore the purpose of this one-shot experimental case study was to evaluate …
Self-and peer assessment of preservice geography teachers' contribution in problem-based learning activities in geography education
A Golightly - International Research in Geographical and …, 2021 - Taylor & Francis
In problem-based learning (PBL), collaboration and productive interactions among group
members are not spontaneous processes. One way to support students in PBL is to integrate …
members are not spontaneous processes. One way to support students in PBL is to integrate …