User profiles for A. Gouin

Katryna A Gouin

Centers for Disease Control and Prevention
Verified email at cdc.gov
Cited by 536

Neurotrophins promote motor neuron survival and are present in embryonic limb bud

CE Henderson, W Camu, C Mettling, A Gouin… - Nature, 1993 - nature.com
Embryonic spinal motor neurons are thought to depend for survival on unidentified factors
secreted both by their peripheral targets and by cells within the central nervous system 1 . The …

[HTML][HTML] Two genomes of highly polyphagous lepidopteran pests (Spodoptera frugiperda, Noctuidae) with different host-plant ranges

A Gouin, A Bretaudeau, K Nam, S Gimenez, JM Aury… - Scientific reports, 2017 - nature.com
Emergence of polyphagous herbivorous insects entails significant adaptation to recognize,
detoxify and digest a variety of host-plants. Despite of its biological and practical importance - …

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

…, RJ Leonard, NJ Vogelaar, L Czyzyk, A Gouin… - Neuron, 1990 - cell.com
The binding site for an open-channel blocker, QX-222, at mouse muscle nicotinic
acetylcholine receptors was probed using site-directed mutagenesis, oocyte expression, and …

Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia

…, M Rozman, M Kulis, D Tamborero, A Gouin… - Genome …, 2014 - genome.cshlp.org
Chronic lymphocytic leukemia (CLL) has heterogeneous clinical and biological behavior.
Whole-genome and -exome sequencing has contributed to the characterization of the …

MindTheGap: integrated detection and assembly of short and long insertions

G Rizk, A Gouin, R Chikhi, C Lemaitre - Bioinformatics, 2014 - academic.oup.com
Motivation: Insertions play an important role in genome evolution. However, such variants are
difficult to detect from short-read sequencing data, especially when they exceed the paired-…

Makespan minimisation on parallel batch processing machines with non-identical job sizes and release dates

…, ML Espinouse, MD Mascolo, A Gouin - International Journal of …, 2012 - Taylor & Francis
The problem we study in this paper arises from the washing step of hospital sterilisation
services. Washers in the washing step are capable of handling more than one medical device …

[HTML][HTML] Whole-genome re-sequencing of non-model organisms: lessons from unmapped reads

A Gouin, F Legeai, P Nouhaud, A Whibley, JC Simon… - Heredity, 2015 - nature.com
Unmapped reads are often discarded from the analysis of whole-genome re-sequencing,
but new biological information and insights can be uncovered through their analysis. In this …

Disentangling the causes for faster-X evolution in aphids

…, F Legeai, N Prunier-Leterme, A Gouin… - Genome Biology and …, 2018 - academic.oup.com
The faster evolution of X chromosomes has been documented in several species, and results
from the increased efficiency of selection on recessive alleles in hemizygous males and/or …

Identifying genomic hotspots of differentiation and candidate genes involved in the adaptive divergence of pea aphid host races

P Nouhaud, M Gautier, A Gouin, J Jaquiéry… - Molecular …, 2018 - Wiley Online Library
Identifying the genomic bases of adaptation to novel environments is a long‐term objective
in evolutionary biology. Because genetic differentiation is expected to increase between …

The use of a checklist improves anaesthesiologists' technical and non-technical performance for simulated malignant hyperthermia management

JB Hardy, A Gouin, C Damm, V Compère… - … Critical Care & Pain …, 2018 - Elsevier
Background Anaesthesiologists may occasionally manage life-threatening operating room (OR)
emergencies. Managing OR emergencies implies real-time analysis of often …