How the ear's works work

AJ Hudspeth - Nature, 1989 - nature.com
The senses of hearing and equilibrium depend on sensory receptors called hair cells which
can detect motions of atomic dimensions and respond more than 100,000 times a second. …

[BOOK][B] Principles of neural science

…, JH Schwartz, TM Jessell, S Siegelbaum, AJ Hudspeth… - 2000 - academia.edu
1 Jordan University of Science and Technology Faculty of Engineering Biomedical Engineering
Department Course Catalog Text Book Page 1 1 Jordan University of Science and Technology …

[HTML][HTML] Making an effort to listen: mechanical amplification in the ear

AJ Hudspeth - Neuron, 2008 - cell.com
The inner ear's performance is greatly enhanced by an active process defined by four
features: amplification, frequency selectivity, compressive nonlinearity, and spontaneous …

Sensitivity, polarity, and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli.

AJ Hudspeth, DP Corey - Proceedings of the National …, 1977 - National Acad Sciences
Hair cells, the primary receptors of the auditory, vestibular, and lateral-line sensory systems,
produce electrical signals in response to mechanical stimulation of their apical hair bundles. …

Essential nonlinearities in hearing

VM Eguíluz, M Ospeck, Y Choe, AJ Hudspeth… - Physical review …, 2000 - APS
Our hearing organ, the cochlea, evidently poises itself at a Hopf bifurcation to maximize tuning
and amplification. We show that in this condition several effects are expected to be generic…

The cellular basis of hearing: the biophysics of hair cells

AJ Hudspeth - Science, 1985 - science.org
A crucial event in the hearing process is the transduction of mechanical stimuli into electrical
signals by hair cells, the sensory receptors of the internal ear. Stimulation results in the …

[PDF][PDF] How hearing happens

AJ Hudspeth - Neuron, 1997 - cell.com
Research on the auditory system has come of age. Al-This hearing loss is ordinarily
permanent, for cochlear though hearing lacks some of the simplifying features hair cells are not …

Movement of microtubules by single kinesin molecules

J Howard, AJ Hudspeth, RD Vale - Nature, 1989 - nature.com
Kinesin is a motor protein that uses energy derived from ATP hydrolysis to move organelles
along microtubules. Using a new technique for measuring the movement produced in vitro …

[HTML][HTML] Vanilloid receptor–related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor

…, MA Martí-Renom, AM Bell, CS Denis, AJ Hudspeth… - Cell, 2000 - cell.com
The detection of osmotic stimuli is essential for all organisms, yet few osmoreceptive proteins
are known, none of them in vertebrates. By employing a candidate-gene approach based …

Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell

J Howard, AJ Hudspeth - Neuron, 1988 - cell.com
Mechanical stimuli are thought to open the transduction channels of a hair cell by tensing
elastic components, the gating springs, that pull directly on the channels. To test this model, we …