How the ear's works work
AJ Hudspeth - Nature, 1989 - nature.com
The senses of hearing and equilibrium depend on sensory receptors called hair cells which
can detect motions of atomic dimensions and respond more than 100,000 times a second. …
can detect motions of atomic dimensions and respond more than 100,000 times a second. …
[BOOK][B] Principles of neural science
…, JH Schwartz, TM Jessell, S Siegelbaum, AJ Hudspeth… - 2000 - academia.edu
1 Jordan University of Science and Technology Faculty of Engineering Biomedical Engineering
Department Course Catalog Text Book Page 1 1 Jordan University of Science and Technology …
Department Course Catalog Text Book Page 1 1 Jordan University of Science and Technology …
[HTML][HTML] Making an effort to listen: mechanical amplification in the ear
AJ Hudspeth - Neuron, 2008 - cell.com
The inner ear's performance is greatly enhanced by an active process defined by four
features: amplification, frequency selectivity, compressive nonlinearity, and spontaneous …
features: amplification, frequency selectivity, compressive nonlinearity, and spontaneous …
Sensitivity, polarity, and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli.
AJ Hudspeth, DP Corey - Proceedings of the National …, 1977 - National Acad Sciences
Hair cells, the primary receptors of the auditory, vestibular, and lateral-line sensory systems,
produce electrical signals in response to mechanical stimulation of their apical hair bundles. …
produce electrical signals in response to mechanical stimulation of their apical hair bundles. …
Essential nonlinearities in hearing
VM Eguíluz, M Ospeck, Y Choe, AJ Hudspeth… - Physical review …, 2000 - APS
Our hearing organ, the cochlea, evidently poises itself at a Hopf bifurcation to maximize tuning
and amplification. We show that in this condition several effects are expected to be generic…
and amplification. We show that in this condition several effects are expected to be generic…
The cellular basis of hearing: the biophysics of hair cells
AJ Hudspeth - Science, 1985 - science.org
A crucial event in the hearing process is the transduction of mechanical stimuli into electrical
signals by hair cells, the sensory receptors of the internal ear. Stimulation results in the …
signals by hair cells, the sensory receptors of the internal ear. Stimulation results in the …
[PDF][PDF] How hearing happens
AJ Hudspeth - Neuron, 1997 - cell.com
Research on the auditory system has come of age. Al-This hearing loss is ordinarily
permanent, for cochlear though hearing lacks some of the simplifying features hair cells are not …
permanent, for cochlear though hearing lacks some of the simplifying features hair cells are not …
Movement of microtubules by single kinesin molecules
J Howard, AJ Hudspeth, RD Vale - Nature, 1989 - nature.com
Kinesin is a motor protein that uses energy derived from ATP hydrolysis to move organelles
along microtubules. Using a new technique for measuring the movement produced in vitro …
along microtubules. Using a new technique for measuring the movement produced in vitro …
[HTML][HTML] Vanilloid receptor–related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor
…, MA Martí-Renom, AM Bell, CS Denis, AJ Hudspeth… - Cell, 2000 - cell.com
The detection of osmotic stimuli is essential for all organisms, yet few osmoreceptive proteins
are known, none of them in vertebrates. By employing a candidate-gene approach based …
are known, none of them in vertebrates. By employing a candidate-gene approach based …
Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell
J Howard, AJ Hudspeth - Neuron, 1988 - cell.com
Mechanical stimuli are thought to open the transduction channels of a hair cell by tensing
elastic components, the gating springs, that pull directly on the channels. To test this model, we …
elastic components, the gating springs, that pull directly on the channels. To test this model, we …