We introduce two large-scale resources for functional analysis of microRNA (miRNA): a decoy
library for inhibiting miRNA function and a sensor library for monitoring microRNA activity. …

Deep sequencing of small RNAs (sRNA-seq) is now the gold standard for small RNA
profiling and discovery. Biases in sRNA-seq have been reported, but their etiology remains …

Material pitting from cavitation bubble collapse is investigated numerically including two-way
fluid–structure interaction (FSI). A hybrid numerical approach which links an …

Background Accurate optical characterisation and removal of small adenomas (<10 mm) at
colonoscopy would allow hyperplastic polyps to be left in situ and surveillance intervals to be …

Bone healing is a complicated process of tissue regeneration that is influenced by multiple
biological and biomechanical processes. In a minority of cases, these physiological …

The legume, Arachis hypogaea produced worldwide is affected by Aspergillus flavus producing
aflatoxin and subsequently influences the economic decline affecting the food industries, …

Considerable details about microRNA (miRNA) biogenesis and regulation have been uncovered,
but little is known about the fate of the miRNA subsequent to target regulation. To gain …

Resistance to checkpoint-blockade treatments is a challenge in the clinic. We found that
although treatment with combined anti-CTLA-4 and anti-PD-1 improved control of established …

In the past decade, medical robotics has gained significant traction within the surgical field.
While the introduction of fully autonomous robotic systems for surgical procedures still …

Recent studies have shown that three-dimensional (3D) culture environments allow the
study of cellular responses in a setting that more closely resembles the in vivo milieu. In this …