User profiles for A. Kostikova

Alexey Kostikov

McGill University
Verified email at mcgill.ca
Cited by 3387

[HTML][HTML] Translational precision medicine: an industry perspective

D Hartl, V de Luca, A Kostikova, J Laramie… - Journal of translational …, 2021 - Springer
In the era of precision medicine, digital technologies and artificial intelligence, drug discovery
and development face unprecedented opportunities for product and business model …

[HTML][HTML] Photoremovable protecting groups in chemistry and biology: reaction mechanisms and efficacy

P Klán, T Solomek, CG Bochet, A Blanc… - Chemical …, 2013 - ACS Publications
Photoremovable (sometimes called photoreleasable, photocleavable or photoactivatable)
protecting groups (PPGs) provide spatial and temporal control over the release of various …

Mapping the world's intact forest landscapes by remote sensing

…, I Glushkov, M Karpachevskiy, A Kostikova… - Ecology and …, 2008 - JSTOR
Protection of large natural forest landscapes is a highly important task to help fulfill different
international strategic initiatives to protect forest biodiversity, to reduce carbon emissions …

Measurement errors should always be incorporated in phylogenetic comparative analysis

D Silvestro, A Kostikova, G Litsios… - Methods in Ecology …, 2015 - Wiley Online Library
The evolution of continuous traits is the central component of comparative analyses in
phylogenetics, and the comparison of alternative models of trait evolution has greatly improved …

[HTML][HTML] Hybridization capture using RAD probes (hyRAD), a new tool for performing genomic analyses on collection specimens

T Suchan, C Pitteloud, NS Gerasimova, A Kostikova… - PloS one, 2016 - journals.plos.org
In the recent years, many protocols aimed at reproducibly sequencing reduced-genome subsets
in non-model organisms have been published. Among them, RAD-sequencing is one of …

[HTML][HTML] Silicon-[18F]Fluorine Radiochemistry: Basics, Applications and Challenges

C Wängler, A Kostikov, J Zhu, J Chin, B Wängler… - Applied Sciences, 2012 - mdpi.com
Silicon-[ 18 F]fluorine (Si- 18 F) radiochemistry has recently emerged alongside other
unconventional approaches such as aluminum- 18 F and boron- 18 F based labeling strategies, …

Quantification of brain cholinergic denervation in Alzheimer's disease using PET imaging with [18F]-FEOBV

M Aghourian, C Legault-Denis, JP Soucy… - Molecular …, 2017 - nature.com
18 F-fluoroethoxybenzovesamicol (FEOBV) is a new PET radiotracer that binds to the
vesicular acetylcholine transporter. In both animals and healthy humans, FEOBV was found …

[HTML][HTML] A proteogenomic view of Parkinson's disease causality and heterogeneity

…, M Dakna, B Bilican, M Dovlatyan, A Kostikova… - npj Parkinson's …, 2023 - nature.com
The pathogenesis and clinical heterogeneity of Parkinson’s disease (PD) have been
evaluated from molecular, pathophysiological, and clinical perspectives. High-throughput …

Where in-vivo imaging meets cytoarchitectonics: the relationship between cortical thickness and neuronal density measured with high-resolution [18F] flumazenil-PET

C la Fougère, S Grant, A Kostikov, R Schirrmacher… - Neuroimage, 2011 - Elsevier
MRI-based measurements of surface cortical thickness (SCT) have become a sensitive tool
to quantify changes in cortical morphology. When comparing SCT to histological cortical …

One-step 18F-labeling of peptides for positron emission tomography imaging using the SiFA methodology

C Wängler, S Niedermoser, J Chin, K Orchowski… - nature protocols, 2012 - nature.com
Here we present a procedure to label peptides with the positron-emitting radioisotope
fluorine-18 (18 F) using the silicon-fluoride acceptor (SiFA) labeling methodology. Positron …