Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …

The brain is worthy of study because it is in charge of behavior. A flurry of recent technical
advances in measuring and quantifying naturalistic behaviors provide an important …

The emerging field of optogenetics allows for optical activation or inhibition of excitable cells.
In 2005, optogenetic proteins were expressed in the nematode Caenorhabditis elegans for …

The ability to acquire large-scale recordings of neuronal activity in awake and unrestrained
animals is needed to provide new insights into how populations of neurons generate animal …

We present an optogenetic illumination system capable of real-time light delivery with high
spatial resolution to specified targets in freely moving Caenorhabditis elegans. A tracking …

Locomotion requires coordinated motor activity throughout an animal's body. In both vertebrates
and invertebrates, chains of coupled central pattern generators (CPGs) are commonly …

The identification and differentiation of a large number of distinct molecular species with high
temporal and spatial resolution is a major challenge in biomedical science. Fluorescence …

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite
interactions that mediate these networks are frequently low affinity and …

Establishing how neural function emerges from network properties is a fundamental problem
in neuroscience 1 . Here, to better understand the relationship between the structure and …

Attachment behaviors recorded in time-sampled observations of 3 groups of mothers were
compared prior to, and 1 and 4 weeks after, infants' hospital discharge. There were no …