Sexually transmitted diseases (STDs) have been generally thought of as a small subset of
infectious diseases, rather than as an important group of diseases that occur in numerous …

The ATP-binding cassette (ABC) transporters belong to the largest known transporter gene
family and translocate a variety of substrates including chemotherapy agents. ABC multidrug …

Context Combination chemotherapy with FOLFIRINOX (oxaliplatin, irinotecan, fluorouracil,
and leucovorin) was shown to be effective in a large phase III trial. Objective The purpose of …

The microbiome can promote or disrupt human health by influencing both adaptive and
innate immune functions. We tested whether bacteria that normally reside on human skin …

Gastric cancer is the fifth most frequently diagnosed cancer and the third leading cause of
death from cancer in the world. Several advances have been made in the staging procedures, …

Somatic mutations of ERBB2 and ERBB3 (which encode HER2 and HER3, respectively)
are found in a wide range of cancers. Preclinical modelling suggests that a subset of these …

The NCCN Clinical Practice Guidelines in Oncology for Gastric Cancer provide evidence-and
consensus-based recommendations for a multidisciplinary approach for the management …

Importance Effective treatment options are limited for patients with advanced, metastatic
esophageal cancer progressing after 2 or more lines of systemic therapy. Objective To evaluate …

Esophageal cancer is the sixth most common cause of cancer deaths worldwide.
Adenocarcinoma is more common in North America and Western European countries, originating …

Importance The histiocytic neoplasms Erdheim-Chester disease (ECD) and Langerhans cell
histiocytosis (LCH) are highly enriched forBRAFV600 mutations and have been previously …