Emerging zoonoses with pandemic potential are a stated priority for the global health security
agenda, but endemic zoonoses also have a major societal impact in low-resource settings. …

For more than 100 years, canine rabies vaccination has been available as a tool for rabies
control and elimination. However, domestic dogs still remain a major reservoir for rabies, and …

Livestock production in Africa is key to national economies, food security and rural livelihoods,
and> 85% of livestock keepers live in extreme poverty. With poverty elimination central to …

Landscape heterogeneity plays an important role in disease spread and persistence, but
quantifying landscape influences and their scale dependence is challenging. Studies have …

How acute pathogens persist and what curtails their epidemic growth in the absence of
acquired immunity remains unknown. Canine rabies is a fatal zoonosis that circulates …

Genomic surveillance is an important aspect of contemporary disease management but has
yet to be used routinely to monitor endemic disease transmission and control in low-and …

Background Tens of thousands of people die from dog-mediated rabies annually. Deaths can
be prevented through post-exposure prophylaxis for people who have been bitten, and the …

Thermotolerant vaccines greatly improved the reach and impact of large-scale vaccination
programs to eliminate diseases such as smallpox, polio and rinderpest. A recent study …

Human rabies can be prevented through mass dog vaccination campaigns; however, in
rabies endemic countries, pulsed central point campaigns do not always achieve the …

This study is the first to partially quantify the potential economic benefits that a vaccine, effective
at protecting cattle against malignant catarrhal fever (MCF), could accrue to pastoralists …