The Arctic climate is changing. Permafrost is warming, hydrological processes are changing
and biological and social systems are also evolving in response to these changing …

Biofilms are communal structures of microorganisms encased in an exopolymeric coat that
form on both natural and abiotic surfaces and have been associated with a variety of …

Though reported capture fisheries are dominated by marine production, inland fish and
fisheries make substantial contributions to meeting the challenges faced by individuals, society, …

We undertook a two-stage genome-wide association study (GWAS) of Alzheimer's disease (AD)
involving over 16,000 individuals, the most powerful AD GWAS to date. In stage 1 (3,941 …

The elucidation of breast cancer subgroups and their molecular drivers requires integrated
views of the genome and transcriptome from representative numbers of patients. We present …

Australia, described in Dorothea Mackellar's 1904 poem My Country as the country of ‘drought
and flooding rains’, may be better placed than most to adapt to changes in climate …

We sought to identify new susceptibility loci for Alzheimer's disease through a staged
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …

Risk for late-onset Alzheimer’s disease (LOAD), the most prevalent dementia, is partially
driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association …

Calorie restriction extends lifespan and produces a metabolic profile desirable for treating
diseases of ageing such as type 2 diabetes 1 , 2 . SIRT1, an NAD + -dependent deacetylase, …

A major challenge in predicting Earth's future climate state is to understand feedbacks that
alter greenhouse-gas forcing. Here we synthesize field data from arctic Alaska, showing that …