Psychological consequences of IVF fertilization–Review of research

A Malina, JA Pooley - Annals of Agricultural and Environmental Medicine, 2017 - aaem.pl
Malina A, Pooley JA. Psychological consequences of IVF fertilization – Review of
research. Ann Agric Environ Med. … Malina A. Sex differences among young adults in the …

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

HG Wendel, E Stanchina, JS Fridman, A Malina, S Ray… - Nature, 2004 - nature.com
Evading apoptosis is considered to be a hallmark of cancer, because mutations in apoptotic
regulators invariably accompany tumorigenesis 1 . Many chemotherapeutic agents induce …

Dissecting eIF4E action in tumorigenesis

HG Wendel, RLA Silva, A Malina, JR Mills… - Genes & …, 2007 - genesdev.cshlp.org
Genetically engineered mouse models are powerful tools for studying cancer genes and
validating targets for cancer therapy. We previously used a mouse lymphoma model to …

Psychosocial aspects of infertility and its treatment

A Malina, A Błaszkiewicz, U Owczarz - Ginekologia polska, 2016 - journals.viamedica.pl
Nowadays, more and more couples face impediments associated with conception. Infertility
is related with experiencing psychological problems by both partners. One of the infertility …

Emerging therapeutics targeting mRNA translation

A Malina, JR Mills, J Pelletier - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
A defining feature of many cancers is deregulated translational control. Typically, this occurs
at the level of recruitment of the 40S ribosomes to the 5′-cap of cellular messenger RNAs (…

mTORC1 promotes survival through translational control of Mcl-1

…, F Robert, SMH Chen, A Malina… - Proceedings of the …, 2008 - National Acad Sciences
Activation of the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway is a frequent
occurrence in human cancers and a major promoter of chemotherapeutic resistance. Inhibition …

Repurposing CRISPR/Cas9 for in situ functional assays

A Malina, JR Mills, R Cencic, Y Yan… - Genes & …, 2013 - genesdev.cshlp.org
RNAi combined with next-generation sequencing has proven to be a powerful and cost-effective
genetic screening platform in mammalian cells. Still, this technology has its limitations …

SHLD 2/FAM 35A co‐operates with REV 7 to coordinate DNA double‐strand break repair pathway choice

S Findlay, J Heath, VM Luo, A Malina, T Morin… - The EMBO …, 2018 - embopress.org
DNA double‐strand breaks ( DSB s) can be repaired by two major pathways: non‐homologous
end‐joining ( NHEJ ) and homologous recombination ( HR ). DNA repair pathway choice …

[HTML][HTML] Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage

R Cencic, H Miura, A Malina, F Robert, S Ethier… - PloS one, 2014 - journals.plos.org
The clustered regularly interspaced short palindromic repeat (CRISPR)-associated enzyme
Cas9 is an RNA-guided nuclease that has been widely adapted for genome editing in …

Conjugation of fatty acids with different lengths modulates the antibacterial and antifungal activity of a cationic biologically inactive peptide

A Malina, Y Shai - Biochemical Journal, 2005 - portlandpress.com
Many studies have shown that an amphipathic structure and a threshold of hydrophobicity
of the peptidic chain are crucial for the biological function of AMPs (antimicrobial peptides). …