Impaired protein metabolism: interlinks between obesity, insulin resistance and inflammation

C Guillet, A Masgrau, S Walrand, Y Boirie - Obesity Reviews, 2012 - Wiley Online Library
Metabolic and structural changes in skeletal muscle that accompany obesity are often
associated with the development of insulin resistance. The first events in the pathogenesis of this …

Outcomes after endovascular therapy with procedural sedation vs general anesthesia in patients with acute ischemic stroke: the AMETIS randomized clinical trial

…, C Cognard, A Guyot, C Fernandez, A Masgrau… - JAMA …, 2023 - jamanetwork.com
Importance General anesthesia and procedural sedation are common practice for mechanical
thrombectomy in acute ischemic stroke. However, risks and benefits of each strategy are …

Time‐course changes of muscle protein synthesis associated with obesity‐induced lipotoxicity

A Masgrau, A Mishellany‐Dutour… - The Journal of …, 2012 - Wiley Online Library
Key points • Prolonged obesity leads to ectopic lipid accumulation in non‐adipose tissues,
particularly in skeletal muscles, inducing metabolic dysfunctions (reduced glucose uptake, …

Is protein metabolism changed with obesity?

C Guillet, A Masgrau, Y Boirie - Current Opinion in Clinical …, 2011 - journals.lww.com
Body composition in obesity is characterized by elevated fat mass but also lean body mass
which is considered either increased or decreased (in the case of sarcopenic obesity). Thus …

Bariatric surgery affects obesity-related protein requirements

C Guillet, A Masgrau, A Mishellany-Dutour, A Blot… - Clinical nutrition …, 2020 - Elsevier
Context Following bariatric surgery, protein deficiency intakes are reported in morbidly
obese patients, whereas post-bariatric protein requirements are not specifically defined with …

[HTML][HTML] Impact of an obesogenic diet program on bone densitometry, micro architecture and metabolism in male rat

…, C Lavet, C Guillet, S Walrand, A Masgrau… - Lipids in Health and …, 2012 - Springer
Background The relationships between fat mass and bone tissue are complex and not fully
elucidated. A high-fat/high-sucrose diet has been shown to induce harmful effects on bone …

Distinct roles of the polarity factors Boi1 and Boi2 in the control of exocytosis and abscission in budding yeast

A Masgrau, A Battola, T Sanmartin… - Molecular biology of …, 2017 - Am Soc Cell Biol
Boi1 and Boi2 (Boi1/2) are budding yeast plasma membrane proteins that function in polarized
growth, and in cytokinesis inhibition in response to chromosome bridges via the NoCut …

Exercise training and return to a well‐balanced diet activate the neuregulin 1/ErbB pathway in skeletal muscle of obese rats

…, M Etienne, S Walrand, A Masgrau… - The Journal of …, 2015 - Wiley Online Library
Key points Some studies suggest that neuregulin 1 (NRG1) could be involved in the regulation
of skeletal muscle energy metabolism in rodents. Here we assessed whether unbalanced …

Sedation versus general anaesthesia in endovascular therapy for anterior circulation acute ischaemic stroke: the multicentre randomised controlled AMETIS trial study …

…, F Verdonk, E Caumon, A Masgrau… - BMJ open, 2019 - bmjopen.bmj.com
Introduction Endovascular thrombectomy is the standard of care for anterior circulation acute
ischaemic stroke (AIS) secondary to emergent large vessel occlusion in patients who qualify…

Nutritional and exercise interventions variably affect estrogen receptor expression in the adipose tissue of male rats

L Metz, M Gerbaix, A Masgrau, C Guillet, S Walrand… - Nutrition Research, 2016 - Elsevier
Energy-dense food consumption and lack of physical activity are implicated in the development
of the current obesity epidemic. The role of estrogen in adiposity and fuel partitioning is …