Here we report the Simons Genome Diversity Project data set: high quality genomes from 300
individuals from 142 diverse populations. These genomes include at least 5.8 million base …

Genome-wide association studies (GWAS) have laid the foundation for investigations into the
biology of complex traits, drug development and clinical guidelines. However, the majority …

INTRODUCTION The consensus view on the peopling of the Americas is that ancestors of
modern Native Americans entered the Americas from Siberia via the Bering Land Bridge and …

The Tyrolean Iceman, a 5,300-year-old Copper age individual, was discovered in 1991 on
the Tisenjoch Pass in the Italian part of the Ötztal Alps. Here we report the complete genome …

Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-wide
variation from this region remain largely uncharacterized. We studied genomic …

Most ancient specimens contain very low levels of endogenous DNA, precluding the shotgun
sequencing of many interesting samples because of cost. Ancient DNA (aDNA) libraries …

Hispanic/Latino populations possess a complex genetic structure that reflects recent admixture
among and potentially ancient substructure within Native American, European, and West …

The Caribbean basin is home to some of the most complex interactions in recent history
among previously diverged human populations. Here, we investigate the population genetic …

North African populations are distinct from sub-Saharan Africans based on cultural, linguistic,
and phenotypic attributes; however, the time and the extent of genetic divergence between …

South America has a complex demographic history shaped by multiple migration and
admixture events in pre- and post-colonial times. Settled over 14,000 years ago by Native …