[HTML][HTML] Fungicide-Driven Evolution and Molecular Basis of Multidrug Resistance in Field Populations of the Grey Mould Fungus Botrytis cinerea
M Kretschmer, M Leroch, A Mosbach, AS Walker… - PLoS …, 2009 - journals.plos.org
The grey mould fungus Botrytis cinerea causes losses of commercially important fruits,
vegetables and ornamentals worldwide. Fungicide treatments are effective for disease control, …
vegetables and ornamentals worldwide. Fungicide treatments are effective for disease control, …
A gapless genome sequence of the fungus Botrytis cinerea
JAL Van Kan, JHM Stassen, A Mosbach… - Molecular plant …, 2017 - Wiley Online Library
Following earlier incomplete and fragmented versions of a genome sequence for the grey
mould Botrytis cinerea, a gapless, near‐finished genome sequence for B. cinerea strain B05.…
mould Botrytis cinerea, a gapless, near‐finished genome sequence for B. cinerea strain B05.…
The ABC transporter BcatrB from Botrytis cinerea exports camalexin and is a virulence factor on Arabidopsis thaliana
…, A Buchala, M Kretschmer, A Mosbach… - The Plant …, 2009 - Wiley Online Library
Arabidopsis thaliana is known to produce the phytoalexin camalexin in response to abiotic
and biotic stress. Here we studied the mechanisms of tolerance to camalexin in the fungus …
and biotic stress. Here we studied the mechanisms of tolerance to camalexin in the fungus …
[HTML][HTML] CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in …
…, D Scheuring, F Willmund, A Mosbach… - PLoS …, 2020 - journals.plos.org
CRISPR/Cas has become the state-of-the-art technology for genetic manipulation in diverse
organisms, enabling targeted genetic changes to be performed with unprecedented …
organisms, enabling targeted genetic changes to be performed with unprecedented …
[HTML][HTML] Anilinopyrimidine Resistance in Botrytis cinerea Is Linked to Mitochondrial Function
A Mosbach, D Edel, AD Farmer, S Widdison… - Frontiers in …, 2017 - frontiersin.org
Crop protection anilinopyrimidine (AP) fungicides were introduced more than 20 years ago
for the control of a range of diseases caused by ascomycete plant pathogens, and in …
for the control of a range of diseases caused by ascomycete plant pathogens, and in …
[HTML][HTML] Sphingolipid metabolism is dysregulated at transcriptomic and metabolic levels in the spinal cord of an animal model of amyotrophic lateral sclerosis
…, V Croixmarie, A Bouscary, A Mosbach… - Frontiers in molecular …, 2018 - frontiersin.org
Lipid metabolism is drastically dysregulated in amyotrophic lateral sclerosis and impacts
prognosis of patients. Animal models recapitulate alterations in the energy metabolism, …
prognosis of patients. Animal models recapitulate alterations in the energy metabolism, …
Living colors in the gray mold pathogen Botrytis cinerea: codon-optimized genes encoding green fluorescent protein and mCherry, which exhibit bright fluorescence
…, P Schneider, A Mosbach… - Applied and …, 2011 - Am Soc Microbiol
The green fluorescent protein (GFP) and its variants have been widely used in modern
biology as reporters that allow a variety of live-cell imaging techniques. So far, GFP has rarely …
biology as reporters that allow a variety of live-cell imaging techniques. So far, GFP has rarely …
[HTML][HTML] A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria tritici
D Steinhauer, M Salat, R Frey, A Mosbach… - PLoS …, 2019 - journals.plos.org
Succinate dehydrogenase inhibitor (SDHI) fungicides are widely used for the control of a
broad range of fungal diseases. This has been the most rapidly expanding fungicide group in …
broad range of fungal diseases. This has been the most rapidly expanding fungicide group in …
[HTML][HTML] Ambroxol hydrochloride improves motor functions and extends survival in a mouse model of familial amyotrophic lateral sclerosis
A Bouscary, C Quessada, A Mosbach… - Frontiers in …, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a multifactorial and fatal neurodegenerative disease.
Growing evidence connects sphingolipid metabolism to the pathophysiology of ALS. In …
Growing evidence connects sphingolipid metabolism to the pathophysiology of ALS. In …
[HTML][HTML] Physics-informed deep learning characterizes morphodynamics of Asian soybean rust disease
H Cavanagh, A Mosbach, G Scalliet, R Lind… - Nature …, 2021 - nature.com
Medicines and agricultural biocides are often discovered using large phenotypic screens
across hundreds of compounds, where visible effects of whole organisms are compared to …
across hundreds of compounds, where visible effects of whole organisms are compared to …