[HTML][HTML] Applications of MALDI-MS/MS-based proteomics in biomedical research
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is one of the
most widely used techniques in proteomics to achieve structural identification and …
most widely used techniques in proteomics to achieve structural identification and …
[HTML][HTML] Recent advances in gastric cancer early diagnosis
L Necula, L Matei, D Dragu, AI Neagu… - World journal of …, 2019 - ncbi.nlm.nih.gov
Gastric cancer (GC) remains an important cause of cancer death worldwide with a high
mortality rate due to the fact that the majority of GC cases are diagnosed at an advanced stage …
mortality rate due to the fact that the majority of GC cases are diagnosed at an advanced stage …
[HTML][HTML] Omics-based investigations of breast cancer
Breast cancer (BC) is characterized by an extensive genotypic and phenotypic heterogeneity.
In-depth investigations into the molecular bases of BC phenotypes, carcinogenesis, …
In-depth investigations into the molecular bases of BC phenotypes, carcinogenesis, …
Tissue engineering by self-assembly of cells printed into topologically defined structures
…, C Norotte, B Damon, F Marga, A Neagu… - … Engineering Part A, 2008 - liebertpub.com
Understanding the principles of biological self-assembly is indispensable for developing
efficient strategies to build living tissues and organs. We exploit the self-organizing capacity of …
efficient strategies to build living tissues and organs. We exploit the self-organizing capacity of …
Engineering biological structures of prescribed shape using self-assembling multicellular systems
K Jakab, A Neagu, V Mironov… - Proceedings of the …, 2004 - National Acad Sciences
Self-assembly is a fundamental process that drives structural organization in both inanimate
and living systems. It is in the course of self-assembly of cells and tissues in early …
and living systems. It is in the course of self-assembly of cells and tissues in early …
[HTML][HTML] Higgs physics at the CLIC electron–positron linear collider
…, D Moya, RM Münker, A Münnich, AT Neagu… - The European Physical …, 2017 - Springer
The Compact Linear Collider (CLIC) is an option for a future\({\mathrm {e}^{+}}{\mathrm {e}^{-}}\)
collider operating at centre-of-mass energies up to\(3\,\text {TeV}\), providing sensitivity …
collider operating at centre-of-mass energies up to\(3\,\text {TeV}\), providing sensitivity …
Antibacterial activity and proposed action mechanism of a new class of synthetic tricyclic flavonoids
This study reports on the inhibitory and bactericidal properties of a new synthetized flavonoid.
Tricyclic flavonoid 1 has been synthesized through a two‐step reaction sequence. The …
Tricyclic flavonoid 1 has been synthesized through a two‐step reaction sequence. The …
[HTML][HTML] Applications of tandem mass spectrometry (MS/MS) in protein analysis for biomedical research
AN Neagu, M Jayathirtha, E Baxter, M Donnelly… - Molecules, 2022 - mdpi.com
Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …
methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted …
[HTML][HTML] Proteomics-based identification of dysregulated proteins in breast cancer
Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
[HTML][HTML] A novel synthetic flavonoid with potent antibacterial properties: In vitro activity and proposed mode of action
The emergence of pathogenic multidrug-resistant bacteria demands new approaches in
finding effective antibacterial agents. Synthetic flavonoids could be a reliable solution due to …
finding effective antibacterial agents. Synthetic flavonoids could be a reliable solution due to …