Areas of life sciences research that were previously distant from each other in ideology,
analysis practices and toolkits, such as microbial ecology and personalized medicine, have all …

▪ Abstract The genomes from three mammals (human, mouse, and rat), two worms, and
several yeasts have been sequenced, and more genomes will be completed in the near future …

To study the genome-wide impact of transposable elements (TEs) on the evolution of protein-coding
regions, we examined 13 799 human genes and found 533 (∼4%) cases of TEs …

Galaxy (homepage: https://galaxyproject.org , main public server: https://usegalaxy.org ) is a
web-based scientific analysis platform used by tens of thousands of scientists across the …

High-throughput data production technologies, particularly ‘next-generation’ DNA sequencing,
have ushered in widespread and disruptive changes to biomedical research. Making …

HYpothesis testing using PHYlogenies (HyPhy) is a scriptable, open-source package for
fitting a broad range of evolutionary models to multiple sequence alignments, and for …

Here, we describe a tool suite that functions on all of the commonly known FASTQ format
variants and provides a pipeline for manipulating next generation sequencing data taken from …

Replication is the cornerstone of a cumulative science [1]. However, new tools and
technologies, massive amounts of data, interdisciplinary approaches, and the complexity of the …

The genetic structure of the indigenous hunter-gatherer peoples of southern Africa, the oldest
known lineage of modern human, is important for understanding human diversity. Studies …

Galaxy ( https://galaxyproject.org ) is a web-based computational workbench used by tens
of thousands of scientists across the world to analyze large biomedical datasets. Since 2005, …