Essentially all organisms from bacteria to humans are mechanosensitive. Physical forces
regulate a large array of physiological processes, and dysregulation of mechanical responses …

Mechanical forces are crucial to the regulation of cell and tissue morphology and function. At
the cellular level, forces influence cytoskeletal organization, gene expression, proliferation, …

Vascular smooth muscle cell (SMC) phenotypic modulation plays a key role in
atherosclerosis and is classically defined as a switch from a ‘contractile’phenotype to a ‘synthetic’…

When mammalian cell cultures or mice are exposed to ionizing radiation in survivable or
lethal amounts, novel mass components are found in the histone H2A region of two-…

The tumor necrosis factor (TNF) superfamily of cytokines includes both soluble and
membrane-bound proteins that regulate immune responses. A member of the human TNF family, …

Narrative inquiry is a methodology that frequently appeals to teachers and teacher educators.
However, this appeal and sense of comfort has advantages and disadvantages. Some …

The JEM–X monitor provides X-ray spectra and imaging with arcminute angular resolution
in the 3 to 35 keV band. The good angular resolution and the low energy response of JEM–X …

In light of the rising prevalence of Alzheimer’s disease (AD), new strategies to prevent, halt,
and reverse this condition are needed urgently. Perturbations of brain network activity are …

Respiratory complex II oxidizes succinate to fumarate as part of the Krebs cycle and reduces
ubiquinone in the electron transport chain. Previous experimental evidence suggested that …

In a climate of increasing emphasis on testing, measurable outcomes, competition and
efficiency, the real lives of children and their teachers are often neglected or are too messy and …