[PDF][PDF] Transcriptional activation of lysosomal exocytosis promotes cellular clearance
…, G Mansueto, C Spampanato, C Puri, A Pignata… - Developmental cell, 2011 - cell.com
Lysosomes are cellular organelles primarily involved in degradation and recycling processes.
During lysosomal exocytosis, a Ca 2+ -regulated process, lysosomes are docked to the …
During lysosomal exocytosis, a Ca 2+ -regulated process, lysosomes are docked to the …
[HTML][HTML] Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape
… , we hypothesized that a bispecific CAR molecule … a CAR that joins a HER2-binding scFv
and an IL13Rα2-binding IL-13 mutein to make a tandem CAR exodomain (TanCAR) and a …
and an IL13Rα2-binding IL-13 mutein to make a tandem CAR exodomain (TanCAR) and a …
Tissue-resident CD8+ T cells drive compartmentalized and chronic autoimmune damage against CNS neurons
D Frieser, A Pignata, L Khajavi, D Shlesinger… - Science translational …, 2022 - science.org
… that a high frequency of brain-infiltrating CD8 + T cells exhibit a T RM -like phenotype in human
autoimmune encephalitis. Using mouse models of neuronal autoimmunity and a … adopt a …
autoimmune encephalitis. Using mouse models of neuronal autoimmunity and a … adopt a …
TEM8/ANTXR1-specific CAR T cells as a targeted therapy for triple-negative breast cancer
TT Byrd, K Fousek, A Pignata, C Szot, H Samaha… - Cancer research, 2018 - AACR
… offer a preclinical proof of concept for immunotherapeutic targeting of TEM8 as a strategy to
… a single light chain of L2 antibody connected by a flexible glycine serine linker, followed by …
… a single light chain of L2 antibody connected by a flexible glycine serine linker, followed by …
Commissural axon navigation in the spinal cord: A repertoire of repulsive forces is in command
H Ducuing, T Gardette, A Pignata… - Seminars in Cell & …, 2019 - Elsevier
… Axons perceive diffusible chemorepulsive cues emanating from a group of guidepost cells
… A group of guidepost cells act as a barrier and confine the axons within a territory. They not …
… A group of guidepost cells act as a barrier and confine the axons within a territory. They not …
Commissural axon navigation: Control of midline crossing in the vertebrate spinal cord by the semaphorin 3B signaling
A Pignata, H Ducuing, V Castellani - Cell Adhesion & Migration, 2016 - Taylor & Francis
… Such a temporal sequence of guidance programs relies on a … to be ensured by SLIT, a gene
encoding a protein which acts … that might be mediated by an as yet-unknown receptor. This …
encoding a protein which acts … that might be mediated by an as yet-unknown receptor. This …
[HTML][HTML] A feasibility study of a tube bundle exchanger with phase change materials: A case study
… storage offers a flexible service to members of a heat district … of a latent heat thermal storage
reactor, integrated in an existing … as a tube bundle heat exchanger in which a commercial-…
reactor, integrated in an existing … as a tube bundle heat exchanger in which a commercial-…
A homing system targets therapeutic T cells to brain cancer
H Samaha, A Pignata, K Fousek, J Ren, FW Lam… - Nature, 2018 - nature.com
… You are using a browser version with limited support for CSS. To obtain the best experience,
we recommend you use a more up to date browser (or turn off compatibility mode in Internet …
we recommend you use a more up to date browser (or turn off compatibility mode in Internet …
[PDF][PDF] A spatiotemporal sequence of sensitization to slits and semaphorins orchestrates commissural axon navigation
A Pignata, H Ducuing, L Boubakar, T Gardette… - Cell reports, 2019 - cell.com
… We set up a paradigm for live-imaging and super-resolution analysis of PlexinA1, Neuropilin-2,
… We uncovered a remarkable program of sensitization to midline cues achieved by unique …
… We uncovered a remarkable program of sensitization to midline cues achieved by unique …
NF-κB subunits RelA and c-Rel selectively control CD4+ T cell function in multiple sclerosis and cancer
… from a role in the initial priming of naive Tconv rather than a … a trend toward a lower
proportion of cytokine-expressing CD8 + T cells in tumor tissues of Rel-icKO mice, suggesting an …
proportion of cytokine-expressing CD8 + T cells in tumor tissues of Rel-icKO mice, suggesting an …