User profiles for A. Pignata

Antonella Pignata

- Verified email at bcm.edu - Cited by 1630

Aurora Pignata

- Verified email at inserm.fr - Cited by 134

[PDF][PDF] Transcriptional activation of lysosomal exocytosis promotes cellular clearance

…, G Mansueto, C Spampanato, C Puri, A Pignata… - Developmental cell, 2011 - cell.com
Lysosomes are cellular organelles primarily involved in degradation and recycling processes.
During lysosomal exocytosis, a Ca 2+ -regulated process, lysosomes are docked to the …

[HTML][HTML] Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

…, M Mukherjee, Z Grada, A Pignata… - The Journal of …, 2016 - Am Soc Clin Investig
… , we hypothesized that a bispecific CAR molecule … a CAR that joins a HER2-binding scFv
and an IL13Rα2-binding IL-13 mutein to make a tandem CAR exodomain (TanCAR) and a

Tissue-resident CD8+ T cells drive compartmentalized and chronic autoimmune damage against CNS neurons

D Frieser, A Pignata, L Khajavi, D Shlesinger… - Science translational …, 2022 - science.org
… that a high frequency of brain-infiltrating CD8 + T cells exhibit a T RM -like phenotype in human
autoimmune encephalitis. Using mouse models of neuronal autoimmunity and a … adopt a

TEM8/ANTXR1-specific CAR T cells as a targeted therapy for triple-negative breast cancer

TT Byrd, K Fousek, A Pignata, C Szot, H Samaha… - Cancer research, 2018 - AACR
… offer a preclinical proof of concept for immunotherapeutic targeting of TEM8 as a strategy to
a single light chain of L2 antibody connected by a flexible glycine serine linker, followed by …

Commissural axon navigation in the spinal cord: A repertoire of repulsive forces is in command

H Ducuing, T Gardette, A Pignata… - Seminars in Cell & …, 2019 - Elsevier
… Axons perceive diffusible chemorepulsive cues emanating from a group of guidepost cells
A group of guidepost cells act as a barrier and confine the axons within a territory. They not …

Commissural axon navigation: Control of midline crossing in the vertebrate spinal cord by the semaphorin 3B signaling

A Pignata, H Ducuing, V Castellani - Cell Adhesion & Migration, 2016 - Taylor & Francis
… Such a temporal sequence of guidance programs relies on a … to be ensured by SLIT, a gene
encoding a protein which acts … that might be mediated by an as yet-unknown receptor. This …

[HTML][HTML] A feasibility study of a tube bundle exchanger with phase change materials: A case study

A Pignata, FD Minuto, A Lanzini, D Papurello - Journal of Building …, 2023 - Elsevier
… storage offers a flexible service to members of a heat district … of a latent heat thermal storage
reactor, integrated in an existing … as a tube bundle heat exchanger in which a commercial-…

A homing system targets therapeutic T cells to brain cancer

H Samaha, A Pignata, K Fousek, J Ren, FW Lam… - Nature, 2018 - nature.com
… You are using a browser version with limited support for CSS. To obtain the best experience,
we recommend you use a more up to date browser (or turn off compatibility mode in Internet …

[PDF][PDF] A spatiotemporal sequence of sensitization to slits and semaphorins orchestrates commissural axon navigation

A Pignata, H Ducuing, L Boubakar, T Gardette… - Cell reports, 2019 - cell.com
… We set up a paradigm for live-imaging and super-resolution analysis of PlexinA1, Neuropilin-2,
… We uncovered a remarkable program of sensitization to midline cues achieved by unique …

NF-κB subunits RelA and c-Rel selectively control CD4+ T cell function in multiple sclerosis and cancer

…, M Plaschka, A Pignata, A Voisin… - Journal of Experimental …, 2024 - rupress.org
… from a role in the initial priming of naive Tconv rather than aa trend toward a lower
proportion of cytokine-expressing CD8 + T cells in tumor tissues of Rel-icKO mice, suggesting an