User profiles for A. Sedeño-Cortés
AE Sedeño-CortésUniversity of Washington Verified email at uw.edu Cited by 1599 |
[HTML][HTML] Comparative cellular analysis of motor cortex in human, marmoset and mouse
…, A Rivkin, WJ Romanow, AE Sedeño-Cortés… - Nature, 2021 - nature.com
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally
conserved across mammals 1 . Here, using high-throughput transcriptomic and epigenomic …
conserved across mammals 1 . Here, using high-throughput transcriptomic and epigenomic …
[HTML][HTML] An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Background A major bottleneck in our understanding of the molecular underpinnings of life
is the assignment of function to proteins. While molecular experiments provide the most …
is the assignment of function to proteins. While molecular experiments provide the most …
[PDF][PDF] Enhancer viruses for combinatorial cell-subclass-specific labeling
Rapid cell type identification by new genomic single-cell analysis methods has not been met
with efficient experimental access to these cell types. To facilitate access to specific neural …
with efficient experimental access to these cell types. To facilitate access to specific neural …
Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse
…, A Rivkin, WJ Romanow, AE Sedeño-Cortés… - BioRxiv, 2020 - biorxiv.org
The primary motor cortex (M1) is essential for voluntary fine motor control and is functionally
conserved across mammals. Using high-throughput transcriptomic and epigenomic profiling …
conserved across mammals. Using high-throughput transcriptomic and epigenomic profiling …
[PDF][PDF] A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation
…, TN Nguyen, J Goldy, AE Sedeno-Cortes… - Cell, 2021 - cell.com
The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles
in perception, cognition, emotion, and learning. We profiled ∼1.3 million cells covering the …
in perception, cognition, emotion, and learning. We profiled ∼1.3 million cells covering the …
[PDF][PDF] Prospective, brain-wide labeling of neuronal subclasses with enhancer-driven AAVs
Labeling and perturbation of specific cell types in multicellular systems has transformed our
ability to understand them. The rapid pace of cell type identification by new single-cell …
ability to understand them. The rapid pace of cell type identification by new single-cell …
[HTML][HTML] Author Correction: Comparative cellular analysis of motor cortex in human, marmoset and mouse
…, A Rivkin, WJ Romanow, AE Sedeño-Cortés… - Nature, 2022 - nature.com
In the version of this article initially published, the Acknowledgements section was incomplete
and has now been amended to include the following:“NIH BRAIN Initiative awards U01 …
and has now been amended to include the following:“NIH BRAIN Initiative awards U01 …
Pitfalls in the application of gene-set analysis to genetics studies
AE Sedeño-Cortés, P Pavlidis - Trends in Genetics, 2014 - cell.com
Gene-set analysis (GSA) (‘enrichment') is a popular approach for the interpretation of
genome-wide association studies (GWASs). GSA is most commonly applied to the analysis of …
genome-wide association studies (GWASs). GSA is most commonly applied to the analysis of …
Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
…, M Reding, C Rimorin, A Ruiz, AE Sedeno-Cortes… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Proper brain function requires the assembly and function of diverse populations of neurons
and glia. Single cell gene expression studies have mostly focused on characterization of …
and glia. Single cell gene expression studies have mostly focused on characterization of …
Enhancer viruses and a transgenic platform for combinatorial cell subclass-specific labeling
The rapid pace of cell type identification by new single-cell analysis methods has not been
met with efficient experimental access to the newly discovered types. To enable flexible and …
met with efficient experimental access to the newly discovered types. To enable flexible and …