[HTML][HTML] Structure of antimicrobial peptides and lipid membranes probed by interface-sensitive X-ray scattering

T Salditt, C Li, A Spaar - Biochimica et Biophysica Acta (BBA) …, 2006 - Elsevier
The conformation and correlations of amphiphilic and antimicrobial peptides and the associated
changes of lipid bilayers can be studied in oriented lipid membranes deposited on solid …

The closure of Pak1‐dependent macropinosomes requires the phosphorylation of CtBP1/BARS

…, E Kakkonen, G Turacchio, C Valente, A Spaar… - The EMBO …, 2008 - embopress.org
Membrane fission is an essential process in membrane trafficking and other cellular functions.
While many fissioning and trafficking steps are mediated by the large GTPase dynamin, …

Sedlin controls the ER export of procollagen by regulating the Sar1 cycle

R Venditti, T Scanu, M Santoro, G Di Tullio, A Spaar… - Science, 2012 - science.org
Newly synthesized proteins exit the endoplasmic reticulum (ER) via coat protein complex II (COPII)
vesicles. Procollagen (PC), however, forms prefibrils that are too large to fit into …

Smoking cessation interventions in COPD: a network meta-analysis of randomised trials

R Strassmann, B Bausch, A Spaar… - European …, 2009 - Eur Respiratory Soc
The aim of this study was to rank order the effectiveness of smoking cessation interventions
for chronic obstructive pulmonary disease (COPD) patients. We searched 10 databases to …

[HTML][HTML] Diffusional encounter of barnase and barstar

A Spaar, C Dammer, RR Gabdoulline, RC Wade… - Biophysical journal, 2006 - cell.com
We present an analysis of trajectories from Brownian dynamics simulations of diffusional
protein-protein encounter for the well-studied system of barnase and barstar. This analysis …

Transport of soluble proteins through the Golgi occurs by diffusion via continuities across cisternae

…, O Martella, D Di Giandomenico, A Fusella, A Spaar… - Elife, 2014 - elifesciences.org
10.7554/eLife.02009.001 The mechanism of transport through the Golgi complex is not
completely understood, insofar as no single transport mechanism appears to account for all of …

[HTML][HTML] Conformation of peptides in lipid membranes studied by x-ray grazing incidence scattering

A Spaar, C Münster, T Salditt - Biophysical journal, 2004 - cell.com
Although the antimicrobial, fungal peptide alamethicin has been extensively studied, the
conformation of the peptide and the interaction with lipid bilayers as well as the mechanism of …

Early versus late pulmonary rehabilitation in chronic obstructive pulmonary disease patients with acute exacerbations: a randomized trial

MA Puhan, A Spaar, M Frey, A Turk, O Brändli… - Respiration, 2012 - karger.com
Background: Around the world, the timing of referral of chronic obstructive pulmonary disease
(COPD) patients for pulmonary rehabilitation differs from immediately after exacerbation (…

[HTML][HTML] Recruitment barriers in a randomized controlled trial from the physicians' perspective–A postal survey

A Spaar, M Frey, A Turk, W Karrer… - BMC medical research …, 2009 - Springer
Background The feasibility of randomized trials often depends on successful patient recruitment.
Although numerous recruitment barriers have been identified it is unclear which of them …

[PDF][PDF] Short range order of hydrocarbon chains in fluid phospholipid bilayers studied by x-ray diffraction from highly oriented membranes

A Spaar, T Salditt - Biophysical journal, 2003 - cell.com
We present a study of the short range ordering of hydrocarbon chains in phospholipid bilayers.
The x-ray peak associated with the hydrocarbon chains has been probed by means of …