The hypersensitive reaction to a pathogen is one of the most efficient defense mechanisms
in nature and leads to the induction of numerous plant genes encoding defense proteins. …

Jasmonates are a growing class of lipid-derived signaling molecules with diverse functions
ranging from the initiation of biotic and abiotic stress responses to the regulation of plant …

The gut microbiome has emerged as an important factor affecting human health and disease.
The recent development of –omics approaches, including phylogenetic marker-based …

Inflammation alters host physiology to promote cancer, as seen in colitis-associated colorectal
cancer (CRC). Here, we identify the intestinal microbiota as a target of inflammation that …

Jasmonic acid (JA) and its precursor 12-oxophytodienoic acid (OPDA) act as plant growth
regulators and mediate responses to environmental cues. To investigate the role of these …

The role of pyoverdin, the main siderophore in iron-gathering capacity produced by Pseudomonas
aeruginosa, in bacterial growth in vivo is controversial, although iron is important for …

The Arabidopsis opr3 mutant is defective in the isoform of 12-oxo-phytodienoate (OPDA)
reductase required for jasmonic acid (JA) biosynthesis. Oxylipin signatures of wounded opr3 …

Intestinal microbial dysbiosis is associated with Crohn’s disease (CD). However, the
mechanisms leading to the chronic mucosal inflammation that characterizes this disease remain …

Jasmonates are derived from oxygenated fatty acids via the octadecanoid pathway and
characterized by a pentacyclic ring structure. They have regulatory function as signaling …

Biosynthesis of the phytohormone jasmonoyl-isoleucine (JA-Ile) requires reduction of the JA
precursor 12-oxo-phytodienoic acid (OPDA) by OPDA reductase 3 (OPR3). Previous …