User profiles for A. Tapinos

Avraam Tapinos

The University of Manchester
Verified email at manchester.ac.uk
Cited by 223

Challenges in the analysis of viral metagenomes

R Rose, B Constantinides, A Tapinos… - Virus …, 2016 - academic.oup.com
Genome sequencing technologies continue to develop with remarkable pace, yet analytical
approaches for reconstructing and classifying viral genomes from mixed samples remain …

[HTML][HTML] Respiratory eukaryotic virome expansion and bacteriophage deficiency characterize childhood asthma

…, C Bachert, S Finotto, T Jartti, A Tapinos… - Scientific Reports, 2023 - nature.com
Asthma development and exacerbation is linked to respiratory virus infections. There is limited
information regarding the presence of viruses during non-exacerbation/infection periods. …

[HTML][HTML] Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

…, A Sanni, M Ajani, JB Reynier, A Tapinos… - Nature …, 2021 - nature.com
Black women across the African diaspora experience more aggressive breast cancer with
higher mortality rates than white women of European ancestry. Although inter-ethnic germline …

Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types from 10,983 cancer patients.

A Everall, A Tapinos, A Hawari, A Cornish, A Sud… - medRxiv, 2023 - medrxiv.org
Whole genome sequencing (WGS) allows exploration of the complete compendium of
oncogenic processes generating characteristic patterns of mutations. Mutational signatures …

[HTML][HTML] A method for comparing multivariate time series with different dimensions

A Tapinos, P Mendes - PloS one, 2013 - journals.plos.org
In many situations it is desirable to compare dynamical systems based on their behavior.
Similarity of behavior often implies similarity of internal mechanisms or dependency on …

Bacteriophage deficiency characterizes respiratory virome dysbiosis in childhood asthma

…, T Jartti, ML Kowalski, AG Sotiropoulos, A Tapinos… - BioRxiv, 2020 - biorxiv.org
Asthma development and persistence is tightly linked to respiratory viruses. Viral presence
is usually interrogated with targeted approaches during periods of disease activity and/or …

[HTML][HTML] A signal processing method for alignment-free metagenomic binning: multi-resolution genomic binary patterns

S Kouchaki, A Tapinos, DL Robertson - Scientific reports, 2019 - nature.com
Algorithms in bioinformatics use textual representations of genetic information, sequences
of the characters A, T, G and C represented computationally as strings or sub-strings. Signal …

[HTML][HTML] Investigation of Salmonella phage–bacteria infection profiles: network structure reveals a gradient of target-range from generalist to specialist phage clones in …

…, N Grdzelishvili, B Stamp, E Herman, A Tapinos… - Viruses, 2021 - mdpi.com
Bacteriophages that lyse Salmonella enterica are potential tools to target and control
Salmonella infections. Investigating the host range of Salmonella phages is a key to understand …

Alignment by numbers: sequence assembly using compressed numerical representations

A Tapinos, B Constantinides, DB Kell, DL Robertson - bioRxiv, 2014 - biorxiv.org
Motivation: DNA sequencing instruments are enabling genomic analyses of unprecedented
scope and scale, widening the gap between our abilities to generate and interpret sequence …

[BOOK][B] Time series data mining in systems biology

A Tapinos - 2013 - search.proquest.com
Abstract Analysis of time series data constitutes an important activity in many scientific
disciplines. Over the last years there has been an increase in the collection of time series data in …