Genes and enzymes involved in deoxysugar biosynthesis in bacteria

A Trefzer, A Bechthold, JA Salas - Natural product reports, 1999 - pubs.rsc.org
… Axel Trefzer,a Jose A. Salasb and Andreas Bechthold*a … Trefzer, S. Stockert, A.
Kirschning and A. … Trefzer, D. Hoffmeister, L. Westrich, G. …

The sequence of a 1.8-Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways

MH Medema, A Trefzer, A Kovalchuk… - Genome Biology and …, 2010 - academic.oup.com
Plasmids are mobile genetic elements that play a key role in the evolution of bacteria by
mediating genome plasticity and lateral transfer of useful genetic information. Although …

Metabolic engineering toward sustainable production of nylon-6

…, HJ Noorman, RAL Bovenberg, AC Trefzer - ACS synthetic …, 2016 - ACS Publications
Nylon-6 is a bulk polymer used for many applications. It consists of the non-natural building
block 6-aminocaproic acid, the linear form of caprolactam. Via a retro-synthetic approach, …

Streptomyces Genetics: A Genomic Perspective

A Paradkar, A Trefzer, R Chakraburtty… - Critical reviews in …, 2003 - Taylor & Francis
Streptomycetes are Gram-positive, soil-inhabiting bacteria of the order Actinomycetales.
These organisms exhibit an unusual, developmentally complex life cycle and produce many …

Systematic transfer of prokaryotic sensors and circuits to mammalian cells

…, L Wroblewska, K Clancy, AC Trefzer… - ACS synthetic …, 2014 - ACS Publications
Prokaryotic regulatory proteins respond to diverse signals and represent a rich resource for
building synthetic sensors and circuits. The TetR family contains >10 5 members that use a …

[PDF][PDF] Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces …

G Weitnauer, A Mühlenweg, A Trefzer, D Hoffmeister… - Chemistry & biology, 2001 - cell.com
Trefzer a, D. Hoffmeister a, RD Su«Mmuth c,d, G. Jung c, K. … Trefzer, G. Drager, A.
Kirschning, C. … Trefzer, D. Hoffmeister, E. Kunzel, S. …

Cloning of an avilamycin biosynthetic gene cluster from Streptomyces viridochromogenes Tü57

S Gaisser, A Trefzer, S Stockert, A Kirschning… - Journal of …, 1997 - Am Soc Microbiol
A 65-kb region of DNA from Streptomyces viridochromogenes Tü57, containing genes
encoding proteins involved in the biosynthesis of avilamycins, was isolated. The DNA sequence …

Technological challenges and milestones for writing genomes

…, JA Schloss, G Stracquadanio, A Trefzer… - Science, 2019 - science.org
Engineering biology with recombinant DNA, broadly called synthetic biology, has progressed
tremendously in the last decade, owing to continued industrialization of DNA synthesis, …

[PDF][PDF] The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: cloning and …

…, K Ichinose, S Domann, B Faust, A Trefzer… - Chemistry & Biology, 2000 - cell.com
Background: Streptomyces fradiae is the principal producer of urdamycin A. The antibiotic
consists of a polyketide-derived aglycone, which is glycosylated with four sugar components, 2…

Introduction: The global south and/in the global north: Interdisciplinary investigations

A Trefzer, JT Jackson, K McKee, K Dellinger - The Global South, 2014 - muse.jhu.edu
This special issue of The Global South encourages power-conscious readings of place that
challenge nation-based models of the Global North (First World) and the Global South (Third …