How bacteria grow and divide while retaining a defined shape is a fundamental question in
microbiology, but technological advances are now driving a new understanding of how the …

Gene essentiality is a founding concept of genetics with important implications in both
fundamental and applied research. Multiple screens have been performed over the years in …

Different environmental stimuli cause bacteria to exchange the sigma subunit in the RNA
polymerase (RNAP) and, thereby, tune their gene expression according to the newly emerging …

A few commonly used non-antibiotic drugs have recently been associated with changes in
gut microbiome composition, but the extent of this phenomenon is unknown. Here, we …

A Western lifestyle with high salt consumption can lead to hypertension and cardiovascular
disease. High salt may additionally drive autoimmunity by inducing T helper 17 (T H 17) cells…

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. However,
the systematic mapping of the interactions between drugs and bacteria has only started …

To minimize the impact of antibiotics, gut microorganisms harbour and exchange antibiotics
resistance genes, collectively called their resistome. Using shotgun sequencing-based …

A systems-level understanding of Gram-positive bacteria is important from both an
environmental and health perspective and is most easily obtained when high-quality, validated …

Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease 1 . Despite this well-known …

As nascent polypeptides exit ribosomes, they are engaged by a series of processing, targeting,
and folding factors. Here, we present a selective ribosome profiling strategy that enables …